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Three-year outcomes of tumor necrosis factor alpha inhibitor therapy in rheumatoid arthritis patients with elevated liver enzymes. [PDF]
Duggal S, Kattamuri L, Sairam S.
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Tumor Necrosis Factor-Alpha Inhibitor-Induced Sarcoid-Like Reaction in a Patient With Juvenile Idiopathic Arthritis: A Case Report. [PDF]
Aung T +4 more
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Tumor necrosis factor alpha in mycobacterial infection
Seminars in Immunology, 2014Tumor necrosis factor alpha (TNF-α) is a critical immune mediator in protection against and pathology of tuberculosis (TB). TNF-α had been found to be associated with TB when it was originally identified as cachexin and until today TB research continues to unveil novel roles of this cytokine of highest relevance for the disease process and for novel ...
Dorhoi, A., Kaufmann, S.
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Role of tumor necrosis factor alpha in asthma
Immunology and Allergy Clinics of North America, 2004Asthma is a heterogeneous disease in which various cytokines orchestrate airway inflammation. Tumor necrosis alpha (TNF-alpha) is a proinflammatory cytokine that has been implicated in the modulation of inflammation in various diseases, including asthma. Although TNF-alpha blocking strategies have been an effective therapeutic modality in diseases such
Babu, K. Suresh +2 more
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Production of Tumor Necrosis Factor Alpha and Hemodialysis
Nephron, 2008The production of TNFα by peripheral blood mononuclear cells (PBMC) was determined in 18 hemodialysis (HD) patients. Blood was taken from each patient before and after an HD treatment. Both pre- and post-HD PBMC produced significantly more TNFα than controls (TNFα units/ml; mean ± SEM; controls 3.1 ± 0.7; pre-HD 9.7 ± 3.9; post-HD 19.8 ± 7.7, p < 0 ...
C, Macdonald +3 more
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The Journal of surgical research, 1992
TNF-alpha (Cachectin) is a cytokine (tissue hormone) synthesized and secreted as a trimeric polypeptide; major producers are the cells of the RES after stimulation, e.g. by endotoxin. Its synthesis is strictly regulated. TNF elicits a great number of cell-specific responses. IL-1 and probably additional mediators cooperate in these effects.
C S, Rock, S F, Lowry
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TNF-alpha (Cachectin) is a cytokine (tissue hormone) synthesized and secreted as a trimeric polypeptide; major producers are the cells of the RES after stimulation, e.g. by endotoxin. Its synthesis is strictly regulated. TNF elicits a great number of cell-specific responses. IL-1 and probably additional mediators cooperate in these effects.
C S, Rock, S F, Lowry
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Piezoelectric biosensor for the determination of Tumor Necrosis Factor Alpha.
Talanta, 2018Tumor Necrosis Factor Alpha (TNFα) is an important marker of inflammatory processes in human body. In the current healthcare, determination of TNFα blood or plasma level is done by Enzyme Linked Immuno-Sorbent Assay (ELISA) as a primary choice method. Piezoelectric immunosensors are analytical platform recording affinity interactions on their surface ...
M. Pohanka
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Tumor Necrosis Factor α and Toxicology
Critical Reviews in Toxicology, 1999The molecular cloning of a group of proteins, collectively referred to as cytokines, and including interleukins, chemokines, growth factors, colony stimulating factors, and tumor necrosis factors, has allowed for the increased understanding of the mechanisms for many disease processes as well as provided strategies for the development of novel ...
M I, Luster +3 more
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