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[Tumor necrosis factor alpha. Biological aspects].
Giornale italiano di chemioterapia, 1989Human Tumor Necrosis Factor-alpha (TNF-alpha) is a multifaceted cytokine mainly produced by activated monocytes or macrophages. Several recent studies have shown that TNF-alpha can exert a variety of in vitro and in vivo effects including: modulation of normal and malignant haemopoiesis, antineoplastic activity, activation of neutrophils, induction of ...
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Priapism after tumor necrosis factor alpha inhibitor use
Clinical Rheumatology, 2015We present a possible important association of tumor necrosis factor-alpha inhibition (TNFa-i) and erectile function in a male patient with rheumatoid arthritis (RA). Long-standing, untreated RA may result in significant physical limitation and disability, however often overlooked is the association between RA and erectile and sexual dysfunction ...
Adam J, Kreitenberg +2 more
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[Tumor necrosis factor-alpha (cachectin)].
Revista clinica espanola, 1989Tumor necrosis factor (TNF) is liberated by macrophages in response to infection. It has different biological effects, namely cytotoxicity on some tumor cell lines, anorexia, hyperlipidemia, and decreases in protein synthesis. It favors immunological responses and produces necrosis of certain tumors.
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Cardiodepression by tumor necrosis factor-alpha.
European cytokine network, 1999Cardiodepressant effects of tumor necrosis factor-alpha (TNF-alpha have been documented in numerous experimental settings in vivo and in vitro. In vivo administration of TNF-alpha mimicks the cardiovascular pattern of sepsis including septic cardiomyopathy.
U, Müller-Werdan +2 more
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Bioassay for Tumor Necrosis Factors-alpha and -beta
Molecular Biotechnology, 2000Tumor necrosis factor (TNF) is a central cytokine in the pathogenesis of septic shock and other inflammatory states. Assay by immunoassay is convenient, but, because of circulating soluble receptors, does not accurately reflect biological activity of the cytokine.
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American Journal of Obstetrics and Gynecology, 2005
Jennifer Donnelly +7 more
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Jennifer Donnelly +7 more
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