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Tumor necrosis factor-alpha inhibitors may increase the need for fine-needle aspiration cytology in axial spondyloarthritis patients. [PDF]
Rev Assoc Med Bras (1992)Sayiner ZA +5 more
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Tumor Necrosis Factor-Alpha Antagonist-Induced Sarcoidosis
JCR: Journal of Clinical Rheumatology, 2010Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Tumor necrosis factor (TNF)-alpha is an important player in granuloma formation, and recent clinical trials have investigated the efficacy of TNF-alpha inhibitors in sarcoidosis. Paradoxically, there are several case reports in the medical literature describing the development of ...
Clementine, Rochelle Robicheaux +5 more
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[Tumor necrosis factor alpha].
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1992TNF-alpha (Cachectin) is a cytokine (tissue hormone) synthesized and secreted as a trimeric polypeptide; major producers are the cells of the RES after stimulation, e.g. by endotoxin. Its synthesis is strictly regulated. TNF elicits a great number of cell-specific responses. IL-1 and probably additional mediators cooperate in these effects.
C S, Rock, S F, Lowry
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Tumor necrosis factor alpha in mycobacterial infection
Seminars in Immunology, 2014Tumor necrosis factor alpha (TNF-α) is a critical immune mediator in protection against and pathology of tuberculosis (TB). TNF-α had been found to be associated with TB when it was originally identified as cachexin and until today TB research continues to unveil novel roles of this cytokine of highest relevance for the disease process and for novel ...
Dorhoi, A., Kaufmann, S.
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Serum Tumor Necrosis Factor-Alpha in Neonatal Sepsis
American Journal of Perinatology, 1997Tumor necrosis factor-alpha (TNF-alpha) is thought to be an important mediator in the pathogenesis of neonatal septicemia. To assess the role of TNF-alpha in neonatal sepsis, serum levels of TNF-alpha were measured in a group of neonates with septicemia and compared with the levels of gestational-postnatal, age-matched healthy controls.
Atici A. +3 more
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Tumor Necrosis Factor α and Toxicology
Critical Reviews in Toxicology, 1999The molecular cloning of a group of proteins, collectively referred to as cytokines, and including interleukins, chemokines, growth factors, colony stimulating factors, and tumor necrosis factors, has allowed for the increased understanding of the mechanisms for many disease processes as well as provided strategies for the development of novel ...
M I, Luster +3 more
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Sensors and Actuators B: Chemical, 2015
Abstract Tumor necrosis factor (TNF)-α promotes rheumatoid arthritis (RA) symptoms, including inflammation and bone erosion. The role of TNF-α in RA is considered to be complex because cytokine is responsible for a wide-range of functions, such as activation of immune cells, stimulation of osteoclast differentiation, and induction of cellular ...
Say, Rıdvan +4 more
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Abstract Tumor necrosis factor (TNF)-α promotes rheumatoid arthritis (RA) symptoms, including inflammation and bone erosion. The role of TNF-α in RA is considered to be complex because cytokine is responsible for a wide-range of functions, such as activation of immune cells, stimulation of osteoclast differentiation, and induction of cellular ...
Say, Rıdvan +4 more
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Immunology Letters, 1994
Eight murine anti-TNF alpha monoclonal antibodies (mAb) were produced after immunization of BALB/c mice with rhTNF alpha. Six of these mAbs were able to neutralize cytotoxic activity of TNF alpha against L929 cells. Two other mAbs had no neutralizing effect. Epitope mapping studies were performed by ELISA and by using a BIAcore system (Pharmacia).
B, Karim +3 more
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Eight murine anti-TNF alpha monoclonal antibodies (mAb) were produced after immunization of BALB/c mice with rhTNF alpha. Six of these mAbs were able to neutralize cytotoxic activity of TNF alpha against L929 cells. Two other mAbs had no neutralizing effect. Epitope mapping studies were performed by ELISA and by using a BIAcore system (Pharmacia).
B, Karim +3 more
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Journal of Periodontology, 1998
Tumor necrosis factor alpha (TNF‐α) is a proinflammatory cytokine that is thought to play a role in the pathogenesis of periodontal disease. TNF‐α production is regulated by many factors, including certain alleles of TNF gene polymorphisms. In the present study, TNF genotypes of 3 bi‐allelic polymorphisms were determined in 32 Caucasian patients with ...
G M, Galbraith +3 more
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Tumor necrosis factor alpha (TNF‐α) is a proinflammatory cytokine that is thought to play a role in the pathogenesis of periodontal disease. TNF‐α production is regulated by many factors, including certain alleles of TNF gene polymorphisms. In the present study, TNF genotypes of 3 bi‐allelic polymorphisms were determined in 32 Caucasian patients with ...
G M, Galbraith +3 more
openaire +2 more sources