Results 11 to 20 of about 717,766 (306)

Tumors in von Hippel–Lindau Syndrome: From Head to Toe—Comprehensive State-of-the-Art Review [PDF]

, 2018
Von Hippel–Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3.
Bhalla, Sanjeev, Ganeshan, Dhakshinamoorthy, Lubner, Meghan G., Menias, Christine O., Pickhardt, Perry J., Ramalingam, Preetha, Sandrasegaran, Kumaresan   +6 more
core   +1 more source

Novel Patient Metastatic Pleural Effusion-Derived Xenograft Model of Renal Medullary Carcinoma Demonstrates Therapeutic Efficacy of Sunitinib

Frontiers in Oncology, 2021
BackgroundRenal medullary carcinoma (RMC) is a rare but aggressive tumor often complicated by early lung metastasis with few treatment options and very poor outcomes.
Alex Q. Lee, Masami Ijiri, Ryan Rodriguez, Regina Gandour-Edwards, Joyce Lee, Clifford G. Tepper, Clifford G. Tepper, Yueju Li, Laurel Beckett, Kit Lam, Neal Goodwin, Noriko Satake   +11 more
doaj   +1 more source

The ambitious role of anti angiogenesis molecules: Turning a cold tumor into a hot one [PDF]

, 2018
In renal cancer emerging treatment options are becoming available and there is a strong need to combine therapies to reformulate and adjourn clinical practice.
Botticelli, A., Marchetti, P., Nuti, M., Rughetti, A., Zizzari, I. G.   +4 more
core   +1 more source

Oncogenic microRNAs characterization in clear cell renal cell carcinoma [PDF]

, 2015
A key challenge for the improvement of clear cell renal cell carcinoma (ccRCC) management could derive from a deeper characterization of the biology of these neoplasms that could greatly improve the diagnosis, prognosis and treatment choice. The aim of
BELLISSIMO, TERESA, CARBONE, Antonio, DELLA ROCCA, Carlo, DI CARLO, ANGELINA, FAZI, Francesco, PALLESCHI, GIOVANNI, PASTORE, ANTONIO LUIGI, PETROZZA, Vincenzo, PORTA, NATALE   +8 more
core   +2 more sources

A Rare Case of Neuroendocrine Tumor Following Radical Nephrectomy

Folia Medica Indonesiana, 2022
Highlights: • Rare occurrence of a large, well-differentiated primary renal neuroendocrine tumor in a young man. • Identifying primary renal NET from the workup and histological examination of renal tumors needs to be done to understand more of this ...
Muhammad Rozaqy Ishaq, Nafis Audrey Febriansyah, Soetojo Soetojo   +2 more
doaj   +1 more source

Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies [PDF]

, 2019
A significantly increased level of the reactive oxygen species (ROS) scavenger glutathione (GSH) has been identified as a hallmark of renal cell carcinoma (RCC). The proposed mechanism for increased GSH levels is to counteract damaging ROS to sustain the
Meierhofer, David, Xiao, Yi
core   +2 more sources

Nefroma mesoblastico congénito: reporte de un caso

Gaceta Médica Boliviana, 2021
El nefroma mesoblastico congénito es un tumor renal infrecuente, pero común en el periodo neonatal. De comportamiento benigno y pronóstico excelente en su variedad clásica pero en el subtipo celular puede presentar recurrencia local, invasión ...
Lorena Arze Aimaretti, Aixa Reusmann, Mariano Boglione, Marcelo Barrenechea, María Laura Galluzzo Mutti, Walter Cacciavillano   +5 more
doaj  

Renal myxoma – a case report of a rare kidney tumor, its differential diagnosis and literature review

IJU Case Reports, 2022
Introduction Myxoma is a rare benign kidney tumor. Only 18 cases have been described in the literature. We report a new case of renal myxoma that arises from the renal parenchyma. Case presentation A 56‐year‐old man, medically free, presented complaining
Rawan Hudairy, Omar Buksh, Rabea Akram, Adel Alammari, Jaudah Al‐Maghrabi, Zuhoor Almansouri   +5 more
doaj   +1 more source

Renal Primitive Neuroectodermal Tumor

Journal of Urological Surgery, 2017
Renal primitive neuroectodermal tumor (PNET) is a rare entity and highly malignant neoplasm. It generally occurs in young adults and children. We report a case of 19-year-old female with the complaint of left flank pain. Ultrasonography showed a tumor of
Hüseyin Çelik, Ahmet Camtosun, İbrahim Dursun, Nusret Akpolat, İsmail Okan Yıldırım   +4 more
doaj   +1 more source

Targeting hypoxia-inducible factor-1α (HIF-1α) in combination with antiangiogenic therapy: a phase I trial of bortezomib plus bevacizumab. [PDF]

, 2014
PurposeWe hypothesized that bortezomib, an agent that suppresses HIF-1α transcriptional activity, when combined with bevacizumab, would obviate the HIF-1α resistance pathway.
Amin, Hesham M, Angelo, Laura S, Falchook, Gerald S, Hess, Kenneth, Hong, David, Howard, Adrienne N, Huang, Mei, Jackson, Edward F, Janku, Filip, Kurzrock, Razelle, Lawhorn, Kristie N, Naing, Aung, Ng, Chaan S, Parkhurst, Kristin L, Tannir, Nizar M, Vishwamitra, Deeksha, Wheler, Jennifer J   +16 more
core   +2 more sources