Results 161 to 170 of about 342,913 (296)

Identification and characterization of a homozygous deletion found in ovarian ascites by representational difference analysis

, 1999
We have performed representational difference analysis (RDA) on DNA from tumor cells and normal fibroblasts isolated from the ascites of a patient with ovarian cancer. Five of six products of the RDA were homozygously deleted from the tumor DNA.
Perry, P, Morrison, H, Gabra, H, Taylor, K J, Watson, J E, Porteous, D J, Rabiasz, G J, Smyth, J F   +7 more
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Tumor suppressor genes, treatments, and survival in US veterans with prostate cancer. [PDF]

Oncologist
Karunanandaa K, Knoche EM, Montgomery RB, Pickett C, Doherty J, Gruber J, Raychaudhuri R, Eaton D, Garraway IP, Rettig MB, Maxwell KN, Schoen MW.   +11 more
europepmc   +1 more source

EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes. [PDF]

Cancer Res, 2023
Huang Y, Durall RT, Luong NM, Hertzler HJ, Huang J, Gokhale PC, Leeper BA, Persky NS, Root DE, Anekal PV, Montero Llopis PDLM, David CN, Kutok JL, Raimondi A, Saluja K, Luo J, Zahnow CA, Adane B, Stegmaier K, Hawkins CE, Ponne C, Le Q, Shapiro GI, Lemieux ME, Eagen KP, French CA.   +25 more
europepmc   +1 more source

Biological function of Cl 2 gene and it’s role in thyroid cancer

, 2011
Here I report data to support a tumor suppressor role of the Cl 2 gene. Indeed, I detected a drastic reduction, of Cl 2 gene expression in almost all thyroid carcinomas analyzed, with respect to normal thyroid, with the lowest expression levels observed ...
Ferraro, Angelo
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Multi-gene DNA methylation profiles of tumor suppressor genes for prognostic prediction in gastric cancer. [PDF]

BMC Cancer
Nam SK, Park J, Kwak Y, Batochir C, Kim EB, Kong SH, Park DJ, Lee HJ, Yang HK, Lee HS.   +9 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Assessment of Promoter Hypermethylation in Tumor Suppressor Genes in Oral Leukoplakia and Oral Submucous Fibrosis. [PDF]

J Pharm Bioallied Sci
Abdul NS, Mhaske S, Afroz S, Nigam S, Jyoti B, Singaraju S, Shivakumar S, Channaiah SG.   +7 more
europepmc   +1 more source