Effects of Low-dose Gamma Radiation on Expression of Apoptotic Genes in Rat Peripheral Blood Lymphocyte [PDF]
Journal of Biomedical Physics and Engineering, 2021 Background: Exposure to high-dose ionizing radiation is known as a human carcinogen factor, but our information about the effects of low-dose ionizing radiation such as occupational exposures is limited.
Zhila Ghorbani, Reza Fardid
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Prognostic impact of p16 and p53 gene expressions in stage 1a epithelial ovarian cancer [PDF]
Obstetrics & Gynecology Science, 2020 Objective Epithelial ovarian cancer (EOC) is rarely detected at stage 1a. Most of the patients have a good prognosis and there are limited factors that affect their survival. In the present study, we evaluated the p16 and p53 gene expressions of stage 1a
Emre Günakan +5 more
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Frontiers in Microbiology, 2022 P53, a well-known tumor suppressor, has been confirmed to regulate the infection of various viruses, including chicken viruses. Our previous study observed antiviral effect of p53 inhibitor Pifithrin-α (PFT-α) on the infection of avian infectious ...
Li Xu +8 more
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Correlation between p53 expression and clinical-pathological characteristics of gastric cancer [PDF]
Vojnosanitetski Pregled, 2011 Backgraund/Aim. Gene p53, or “cell genome keeper”, has a preventive effect on the occurrence of genetic aberrations and prevents abnormal expansion of (tumor) cells. In gastric cancer cells in most cases we register high expression of mutated p53 gene,
Radovanović Dragče +3 more
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Isochromosome der(17)(q10)t(15;17) in acute promyelocytic leukemia resulting in an additional copy of the RARA-PML and loss of one p53 gene: Report of two cases and literature review [PDF]
Vojnosanitetski Pregled, 2019 Introduction. The isochromosome of the long arm of derivative chromosome 17, that originates from the translocation t(15;17) [ider(17)(q10)t(15;17), or ider(17q)] in acute promyelocytic leukemia (APL), is a rare chromosome aberration associated with a ...
Đorđević Vesna +6 more
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Global effect of inauhzin on human p53-responsive transcriptome. [PDF]
PLoS ONE, 2012 Previously, we reported that Inauhzin (INZ) induces p53 activity and suppresses tumor growth by inhibiting Sirt1. However, it remains unknown whether INZ may globally affect p53-dependent gene expression or not.
Jun-Ming Liao +3 more
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Characterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions. [PDF]
PLoS Genetics, 2013 p53 protects us from cancer by transcriptionally regulating tumor suppressive programs designed to either prevent the development or clonal expansion of malignant cells.
Katharina Schlereth +9 more
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Acetylation of carboxyl-terminal domain selectively regulates p53-mediated gene transcriptionn [PDF]
Jichu yixue yu linchuang, 2021 Objective To explore whether carboxyl-terminal domain (CTD) acetylation contributes to selectively regulating p53-mediated transcription of a subset of genes. Methods Based on p53-null lung cancer cell line H1299, a pair of inducible cell strains
YAN Xiao-jun, XU Wen-bin, WANG Dong-lai
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Prognostic value of p16, p53, and pcna in sarcoma and an evaluation of immune infiltration
Journal of Orthopaedic Surgery and Research, 2022 Background p16, p53, and proliferating cell nuclear antigen (pcna) genes play significant roles in many chromatin modifications and have been found to be highly expressed in a variety of tumor tissues.
Dechao Cai +6 more
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Anais Brasileiros de Dermatologia, 2010 As poroceratoses compreendem um grupo de doenças da queratinização epidérmica, hereditárias ou adquiridas, caracterizadas histologicamente pela presença de lamela cornoide.
Tiago Torres +2 more
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