Results 291 to 300 of about 9,826,714 (353)
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Acta Biomaterialia, 2021
The synergistic manipulation of autophagy blocking with tumor targeting and penetration effects to enhance cancer cell killing during photothermal therapy (PTT) remains a substantial challenge. Herein, we fabricated a biomimetic nanoplatform by precisely
Xueqin Huang +10 more
semanticscholar +1 more source
The synergistic manipulation of autophagy blocking with tumor targeting and penetration effects to enhance cancer cell killing during photothermal therapy (PTT) remains a substantial challenge. Herein, we fabricated a biomimetic nanoplatform by precisely
Xueqin Huang +10 more
semanticscholar +1 more source
Strategies for active tumor targeting-an update.
European Journal of Pharmacology, 2021A complete cure for cancer is still the holy grail for scientists. The existing treatment of cancer is primarily focused on surgery, radiation and conventional chemotherapy.
Darshan Vyas +2 more
semanticscholar +1 more source
Current Opinion in Cell Biology, 2003
Several recent scientific and technical developments have made it possible to postulate the use of the 'magic bullet' concept; that is, the identification of specific antigens present on tumor cells that can be targeted either by therapeutic antibodies or by small molecules.
Pantea, Houshmand, Albert, Zlotnik
openaire +2 more sources
Several recent scientific and technical developments have made it possible to postulate the use of the 'magic bullet' concept; that is, the identification of specific antigens present on tumor cells that can be targeted either by therapeutic antibodies or by small molecules.
Pantea, Houshmand, Albert, Zlotnik
openaire +2 more sources
Seminars in Oncology, 2009
Our understanding of the process of tumor angiogenesis has changed significantly since the late 1970s, when vascular endothelial growth factor (VEGF) was first identified as vascular permeability factor and later found to be the major mediator of physiologic and pathologic angiogenesis.
Puja, Gaur +3 more
openaire +2 more sources
Our understanding of the process of tumor angiogenesis has changed significantly since the late 1970s, when vascular endothelial growth factor (VEGF) was first identified as vascular permeability factor and later found to be the major mediator of physiologic and pathologic angiogenesis.
Puja, Gaur +3 more
openaire +2 more sources
Influence of nanomedicine mechanical properties on tumor targeting delivery.
Chemical Society Reviews, 2020Modulating nanomedicine mechanical properties for enhanced drug delivery to tumors has attracted increasing attention in the past few decades. In this tutorial review, we analyze the impact of nanomedicine mechanical properties on in vivo transport ...
Zheng Li +5 more
semanticscholar +1 more source
Self‐Propelled Micro/Nanomotors for Tumor Targeting Delivery and Therapy
Advanced Healthcare Materials, 2020Cancer is still one of the most serious diseases with threats to health and life. Although some advances have been made in targeting delivery of antitumor drugs over the past number of years, there are still many problems needing to be solved, such as ...
Ruyi Lin +3 more
semanticscholar +1 more source
2013
Four decades after the seminal work of Judah Folkman, in 1971, cancer therapies based on the suppression of neo-angiogenesis (Folkman, N Engl J Med 285:1182–1186, 1971) are becoming a reality (Verheul et al., Clin Cancer Res 14(11):3589–3597, 2008).
STAIBANO, STEFANIA +1 more
openaire +2 more sources
Four decades after the seminal work of Judah Folkman, in 1971, cancer therapies based on the suppression of neo-angiogenesis (Folkman, N Engl J Med 285:1182–1186, 1971) are becoming a reality (Verheul et al., Clin Cancer Res 14(11):3589–3597, 2008).
STAIBANO, STEFANIA +1 more
openaire +2 more sources
Hormone Research in Paediatrics, 2007
<i>Background:</i> Pituitary tumors are common and usually grow insidiously over many years. Rarely fatal, treatment still requires multiple cytoreductive surgeries and/or radiation therapy with its attendant side effects. As a disease process of regulatory pathways, pituitary tumors offer numerous potential therapeutic targets, and many ...
openaire +2 more sources
<i>Background:</i> Pituitary tumors are common and usually grow insidiously over many years. Rarely fatal, treatment still requires multiple cytoreductive surgeries and/or radiation therapy with its attendant side effects. As a disease process of regulatory pathways, pituitary tumors offer numerous potential therapeutic targets, and many ...
openaire +2 more sources
Targeting Glioblastoma Tumor Microenvironment
2020Glioblastoma, also referred to as glioblastoma multiforme (GBM), is an aggressive type of brain cancer. The prognosis for GBM is poor with an average medium survival rate of 12-15 months. GBM is highly challenging to treat due to neural stem cells phenotypic variations.
Megan, Butler +2 more
openaire +2 more sources
Biomaterials, 2020
Targeted drug delivery using biological ligands can improve the precision of cancer therapy. However, this active targeting strategy is limited in tumor targeting and penetration abilities due to the paucity and heterogeneous distribution of targeted ...
Yalan Tu +5 more
semanticscholar +1 more source
Targeted drug delivery using biological ligands can improve the precision of cancer therapy. However, this active targeting strategy is limited in tumor targeting and penetration abilities due to the paucity and heterogeneous distribution of targeted ...
Yalan Tu +5 more
semanticscholar +1 more source