Results 41 to 50 of about 2,657,421 (309)

Pyroptosis, a New Breakthrough in Cancer Treatment

open access: yesFrontiers in Oncology, 2021
The way of cell death can be roughly divided into two categories: cell necrosis and PCD(programmed cell death). Pyroptosis is a kind of PCD, its occurrence depends on the gasdermin protein family and it will produce inflammatory response.
Dengqiang Wu   +5 more
doaj   +1 more source

Nuclear Targeting Dynamics of Gold Nanoclusters for Enhanced Therapy of HER2(+) Breast Cancer [PDF]

open access: yes, 2011
Recent advances in fluorescent metal nanoclusters have spurred tremendous interest In nanomedicine due to the ease of fabrication, excellent biocompatibility, and, more Importantly, excellent wavelength-dependent tunability.
Joseph Irudayaraj   +5 more
core   +1 more source

BSA-Coated Gold Nanorods for NIR-II Photothermal Therapy

open access: yesNanoscale Research Letters, 2021
The second near infrared window is considered to be the optimal optical window for medical imaging and therapy as its capability of deep tissue penetration.
Shubi Zhao   +7 more
doaj   +1 more source

Tumor Evolution as a Therapeutic Target [PDF]

open access: yesCancer Discovery, 2017
Abstract Recent technological advances in the field of molecular diagnostics (including blood-based tumor genotyping) allow the measurement of clonal evolution in patients with cancer, thus adding a new dimension to precision medicine: time.
Amirouchene-Angelozzi, Nabil   +2 more
openaire   +3 more sources

Nuclisome : targeting the tumor cell nucleus [PDF]

open access: yes, 2012
The Nuclisome concept builds on a novel two-step targeting strategy with the aim to deliver short-range Auger-electron-emitting radionuclides to nuclear DNA of tumor cells.
Katarina Edwards   +5 more
core   +1 more source

Targeting tumor heterogeneity with neoantigen-based cancer vaccines

open access: yes, 2023
Neoantigen-based cancer vaccines have emerged as a promising immunotherapeutic approach to treat cancer. Nevertheless, the high degree of heterogeneity in tumors poses a significant hurdle for developing a vaccine that targets the therapeutically ...
Chen, Shuxiong   +5 more
core   +1 more source

Molecular Targets for Tumor Radiosensitization [PDF]

open access: yesChemical Reviews, 2009
It is estimated that in 2008 1.4 million patients in North America will be diagnosed with a nonskin form of cancer (www.cancer.org), of which seventy-five percent will receive radiotherapy sometime during the course of their disease. Clearly, radiotherapy continues to serve as a primary cancer treatment modality; consequently, the development of ...
Philip J, Tofilon, Kevin, Camphausen
openaire   +2 more sources

An Engineering Approach to Cancer Therapy Using Systemically Delivered siRNA [PDF]

open access: yes, 2007
The next generation of cancer therapeutics will specifically target processes responsible for the growth and survival of cancer cells. Among the most promising of these molecularly targeted therapeutics are small interfering RNAs (siRNAs). These siRNAs
Bartlett, Derek William
core   +1 more source

Engineering the tumor microenvironment of colorectal cancer [PDF]

open access: yes, 2014
The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
core   +1 more source

The Involvement of Ascorbic Acid in Cancer Treatment

open access: yesMolecules
Vitamin C (VC), also known as ascorbic acid, plays a crucial role as a water-soluble nutrient within the human body, contributing to a variety of metabolic processes.
Di Guo   +8 more
doaj   +1 more source

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