Results 271 to 280 of about 3,547,100 (335)

A targeted antiferromagnetic nanoprobe for ultra‐sensitive magnetic resonance imaging detection of sub‐millimeter esophageal tumors

BMEMat, EarlyView.
We developed a cyclo‐RGD peptide‐conjugated antiferromagnetic nanoparticle (RANP) as a targeted T1 contrast agent. Under 9 T MRI conditions, RANP exhibited an r1 value of 1.88 mM−1 s−1 and a low r2/r1 ratio of 1.84, enabling the detection of esophageal tumors as small as 0.8 mm in vivo. Abstract Early, non‐invasive detection of esophageal cancer at sub‐
Wenkui Mo, Zeyu Liang, Bo Zhang, Lin Xiao, Xun Liu, Zhigao Yi, Shangzhi Xie, Qiyue Wang, Liang Shi, Taobo Luo, Feng Li, Leilei Wu, Yuanzhe Piao, Fangyuan Li, Jian Zeng, Daishun Ling   +15 more
wiley   +1 more source

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Tumor vasculature-targeting nanomedicines.

Acta Biomaterialia, 2021
Uncontrolled tumor growth and subsequent distant metastasis are highly dependent on an adequate nutrient supply from tumor blood vessels, which have relatively different pathophysiological characteristics from those of normal vasculature.
Ying Zhang, Jingni He
semanticscholar   +3 more sources

Effects of radiation on tumor vasculature

Molecular Carcinogenesis, 2021
Radiation has been utilized as a direct cytotoxic tumorcidal modality, however, the effect of radiation on tumor vasculature influences response to anticancer therapies.
T. Yamazaki, K. Young
semanticscholar   +3 more sources

Smart Nanotherapeutic Targeting of Tumor Vasculature.

Accounts of Chemical Research, 2019
The past decades have witnessed the development of a field dedicated to targeting tumor vasculature for cancer therapy. In contrast to conventional chemotherapeutics that need to penetrate into tumor tissues for killing tumor cells, the agents targeting ...
Zifu Li, Chunzhi Di, Suping Li, Xiangliang Yang, Guangjun Nie   +4 more
semanticscholar   +4 more sources

Emerging nanotechnological approaches to regulating tumor vasculature for cancer therapy.

Journal of Controlled Release, 2023
Abnormal angiogenesis stands for one of the most striking manifestations of malignant tumor. The pathologically and structurally abnormal tumor vasculature facilitates a hostile tumor microenvironment, providing an ideal refuge exclusively for cancer ...
Chunling Wang, Junchao Xu, Yinlong Zhang, Guangjun Nie   +3 more
semanticscholar   +1 more source

Chemotherapy targeted to tumor vasculature

Current Opinion in Oncology, 1998
Vasculature-targeted chemotherapy--the destruction of tumor blood vessels with cytotoxic agents--makes use of biochemical differences between angiogenic and resting blood vessels. This approach may minimize or eliminate some of the problems associated with conventional solid-tumor targeting, such as poor tissue penetration and drug resistance ...
W, Arap, R, Pasqualini, E, Ruoslahti
openaire   +2 more sources

Jet‐Lagged Nanoparticles Enhanced Immunotherapy Efficiency through Synergistic Reconstruction of Tumor Microenvironment and Normalized Tumor Vasculature

Advanced Healthcare Materials, 2020
Lactic acid (LA), an anaerobic glycolysis metabolite normally oversecreted by tumor cells, can inhibit the activity of T cells and stimulate the rapid proliferation and migration of tumor endothelial cells (TECs), thereby limiting the synergistic ...
Zhijie Jiang, Hui Xiong, Shan Yang, Yun Lu, Yudi Deng, Jianxu Yao, Jing Yao   +6 more
semanticscholar   +1 more source

Radiation Damage to Tumor Vasculature Initiates a Program that Promotes Tumor Recurrences.

International Journal of Radiation Oncology, Biology, Physics, 2020
This review, mostly of preclinical data, summarizes the evidence that radiation at doses relevant to radiotherapy initiates a pathway that promotes the reconstitution of the tumor vasculature leading to tumor recurrence.
J. Brown
semanticscholar   +1 more source

Magnetic resonance imaging of tumor vasculature

Thrombosis and Haemostasis, 2003
SummaryAngiogenic activity and formation of a vascular network facilitate tumor perfusion and play a critical role in tumor growth and metastasis. Tumor vasculature may be visualized by means of parametric imaging of specific morphological and physiological characteristics that collectively describe its properties.
Hadassa, Degani, Maya, Chetrit-Dadiani, Liora, Bogin, Edna, Furman-Haran   +3 more
openaire   +2 more sources

Nanoparticle-mediated internal radioisotope therapy to locally increase the tumor vasculature permeability for synergistically improved cancer therapies.

Biomaterials, 2019
The limited tumor specific uptake of nanoparticles is one of major bottlenecks for clinical translation of nanoscale therapeutics. Herein, we propose a strategy using internal radioisotope therapy (RIT) delivered by liposomal nanoparticles to improve the
Chao Liang, Y. Chao, Xuan Yi, Jun Xu, Liangzhu Feng, Qi Zhao, Kai Yang, Zhuang Liu   +7 more
semanticscholar   +1 more source