Results 251 to 260 of about 1,359,527 (294)
Obesity, EarlyView.ABSTRACT Objective Incretin‐based obesity therapies (IBTs), especially GLP‐1 receptor agonists (GLP‐1 RAs), effectively treat obesity and improve comorbidities. However, their impact on energy metabolism is unclear. A recent case of acute generalized muscle weakness in a patient with mitochondrial myopathy after tirzepatide exposure raises concerns ...
Bryn Falahee +2 more
wiley +1 more source
Fetal Intracranial Hemorrhage: What to Tell Expecting Parents?
Prenatal Diagnosis, EarlyView.ABSTRACT To review the classification, epidemiology, etiology, prenatal diagnostic approach, and neurodevelopmental outcomes of fetal intracranial hemorrhage (ICH), and to provide clinicians with a practical, fetal‐specific framework for investigating and counseling families facing this diagnosis.
Shiri Shinar, Yada Kunpalin, Elka Miller
wiley +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Tumor vasculature-targeting nanomedicines
Acta Biomaterialia, 2021Uncontrolled tumor growth and subsequent distant metastasis are highly dependent on an adequate nutrient supply from tumor blood vessels, which have relatively different pathophysiological characteristics from those of normal vasculature. Obviously, strategies targeting tumor vasculature, such as anti-angiogenic drugs and vascular disrupting agents ...
Ying, Zhang, Jingni, He
exaly +3 more sources
Neuropilins in the Context of Tumor Vasculature [PDF]
International Journal of Molecular Sciences, 2019 Neuropilin-1 and Neuropilin-2 form a small family of plasma membrane spanning receptors originally identified by the binding of semaphorin and vascular endothelial growth factor. Having no cytosolic protein kinase domain, they function predominantly as co-receptors of other receptors for various ligands.
Johannes Eble, Stephan Niland
exaly +3 more sources
Therapeutic targeting of the tumor vasculature
Seminars in Radiation Oncology, 2004A functional tumor vasculature is essential for tumor growth and metastasis and makes an attractive target for therapy. Both antiangiogenic and antivascular approaches are being developed for this purpose. In this article, the current antiangiogenic and antivascular approaches to cancer therapy, potential for their combination with radiotherapy ...
Gillian M, Tozer, Roy, Bicknell
openaire +2 more sources
Chemotherapy targeted to tumor vasculature
Current Opinion in Oncology, 1998Vasculature-targeted chemotherapy--the destruction of tumor blood vessels with cytotoxic agents--makes use of biochemical differences between angiogenic and resting blood vessels. This approach may minimize or eliminate some of the problems associated with conventional solid-tumor targeting, such as poor tissue penetration and drug resistance ...
W, Arap, R, Pasqualini, E, Ruoslahti
openaire +2 more sources
There will be blood: targeting tumor vasculature
Blood, 2009Extradomain B of fibronectin (ED-B FN) is expressed in the vasculature of hematopoietic malignancies and appears to be an effective target for monoclonal antibody–based therapies.
Nathan, Fowler, Anas, Younes
openaire +2 more sources
Tumors of the pulmonary vasculature
Cardiology Clinics, 2004Most primary tumors of the pulmonary vasculature are sarcomas arising in the main pulmonary arteries and veins with high mortality rates. Pulmonary artery sarcoma is far more prevalent than its venous counterpart, though both are rare. Pulmonary capillary hemangiomatosis is a rare low-grade tumor or tumor-like lesion of the pulmonary capillaries that ...
openaire +2 more sources
Tumor vasculature as target for therapeutic intervention
Expert Opinion on Investigational Drugs, 2010Solid tumors rely on efficient oxygen and nutrients transport for their growth, development and survival. Many tumors can stimulate new blood vessel formation. Because this angiogenic vasculature is aberrant from normal host vasculature, several strategies have been explored that specifically target tumor blood vessels.Over the past decade, many ...
Fens, M.H.A.M. +2 more
openaire +3 more sources
Antibody-based targeting of the tumor vasculature
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2007Conventional cytotoxic therapies of cancer often suffer from a lack of specificity, leading to a poor therapeutic index and considerable toxicities to normal organs. An elegant way to overcome the disadvantages of conventional tumor therapy is the selective delivery of therapeutics to the tumor site by their conjugation to a carrier molecule specific ...
Schliemann C, Neri D
openaire +3 more sources