Results 51 to 60 of about 3,547,100 (335)

The ambitious role of anti angiogenesis molecules: Turning a cold tumor into a hot one [PDF]

, 2018
In renal cancer emerging treatment options are becoming available and there is a strong need to combine therapies to reformulate and adjourn clinical practice.
Botticelli, A., Marchetti, P., Nuti, M., Rughetti, A., Zizzari, I. G.   +4 more
core   +1 more source

Neuropilins in the Context of Tumor Vasculature

International Journal of Molecular Sciences, 2019
Neuropilin-1 and Neuropilin-2 form a small family of plasma membrane spanning receptors originally identified by the binding of semaphorin and vascular endothelial growth factor.
S. Niland, J. Eble
semanticscholar   +1 more source

Tumor metastasis and the lymphatic vasculature

International Journal of Cancer, 2009
AbstractTumor‐associated lymphatic vessels act as a conduit by which disseminating tumor cells access regional lymph nodes and form metastases there. Lymph node metastasis is of major prognostic significance for many types of cancer, although lymph node metastases are themselves rarely life‐threatening.
Sleeman, J. P., Thiele, W.
openaire   +3 more sources

Chorioallantoic membrane assay as model for angiogenesis in tissue engineering : focus on stem cells [PDF]

, 2020
Tissue engineering aims to structurally and functionally regenerate damaged tissues, which requires the formation of new blood vessels that supply oxygen and nutrients by the process of angiogenesis.
Bronckaers, Annelies, De Spiegelaere, Ward, Lambrichts, Ivo, Lo Monaco, Melissa, Merckx, Greet, Tay, Hanna, van Zandvoort, Marc   +6 more
core   +3 more sources

TET2-mediated tumor cGAS triggers endothelial STING activation to regulate vasculature remodeling and anti-tumor immunity in liver cancer

Nature Communications
Induction of tumor vascular normalization is a crucial measure to enhance immunotherapy efficacy. cGAS-STING pathway is vital for anti-tumor immunity, but its role in tumor vasculature is unclear.
Hongwei Lv, Qianni Zong, Cian Chen, Guishuai Lv, Wei Xiang, Fuxue Xing, GuoQing Jiang, Bing Yan, Xiaoyan Sun, Yue Ma, Liang Wang, Zixin Wu, Xiuliang Cui, Hongyang Wang, Wen Yang   +14 more
semanticscholar   +1 more source

Normalization of Tumor Vasculature by Oxygen Microbubbles with Ultrasound

Theranostics, 2019
Tumor microenvironment influences the efficacy of anti-cancer therapies. The dysfunctional tumor vasculature limits the efficiency of oxygenation and drug delivery to reduce treatment outcome.
Yi-Ju Ho, Shu-Wei Chu, En-Chi Liao, Ching-Hsiang Fan, H. Chan, Kuo-Chen Wei, C. Yeh   +6 more
semanticscholar   +1 more source

A Facile Method to Probe the Vascular Permeability of Nanoparticles in Nanomedicine Applications

Scientific Reports, 2017
The effectiveness of nanoparticles (NP) in nanomedicine depends on their ability to extravasate from vasculature towards the target tissue. This is determined by their permeability across the endothelial barrier.
Yan Teck Ho, Giulia Adriani, Sebastian Beyer, Phan-Thien Nhan, Roger D. Kamm, James Chen Yong Kah   +5 more
doaj   +1 more source

Quantitative Immunohistochemistry for Evaluating the Distribution of Ki67 and Other Biomarkers in Tumor Sections and Use of the Method to Study Repopulation in Xenografts after Treatment with Paclitaxel

Neoplasia: An International Journal for Oncology Research, 2012
Background: Surviving cells may repopulate tumors between courses of chemotherapy, thereby reducing the effectiveness of treatment. Using a novel quantitative method, we characterize the influence of the tumor microenvironment on repopulation of ...
Andrea S. Fung, James Jonkman, Ian F. Tannock   +2 more
doaj   +1 more source

Flow-correlated dilution of a regular network leads to a percolating network during tumor induced angiogenesis

, 2009
We study a simplified stochastic model for the vascularization of a growing tumor, incorporating the formation of new blood vessels at the tumor periphery as well as their regression in the tumor center.
Paul, Raja
core   +1 more source

Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells [PDF]

, 2016
Indexación: Web of ScienceTumor angiogenesis is widely recognized as one of the hallmarks of cancer. Consequently, during the last decades the development and testing of commercial angiogenic inhibitors has been a central focus for both basic and ...
Carrasco-Avino, G, Corvalan, AH, Owen, GI, Pinto, MP, Sotomayor, P   +4 more
core   +1 more source