Results 241 to 250 of about 3,141,404 (351)

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li   +9 more
wiley   +1 more source

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

open access: yesAdvanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias   +23 more
wiley   +1 more source

Investigation of Epstein-Barr virus or human cytomegalovirus in pediatric gliomas: A retrospective single-center study from Tunisia. [PDF]

open access: yesBiochem Biophys Rep
Missaoui N   +10 more
europepmc   +1 more source

Tumor infection with human herpes viruses and features of peripheral blood lymphocyte subset composition in patients with uveal melanoma

open access: diamond
E. V. Svetlova   +6 more
openalex   +2 more sources

The Initiation of Virus Protein Synthesis in Krebs Ascites Tumor Cells Infected with EMC Virus

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1962
I M, KERR   +3 more
openaire   +2 more sources

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

Immunotherapy for Cancer: Current Advances and Future Directions. [PDF]

open access: yesInt J Mol Sci
Saxena T   +12 more
europepmc   +1 more source

Newcastle disease virus infection induces parthanatos in tumor cells via calcium waves

open access: gold
Yang Qu   +10 more
openalex   +1 more source

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