Results 251 to 260 of about 269,778 (316)

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Macrophage Immune Responses in Viral Infections: Functional Plasticity and Therapeutic Targeting. [PDF]

J Microbiol Biotechnol
Kim J, Lee H, Jang YS.
europepmc   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Epstein-Barr virus (EBV)-associated smooth muscle tumor of the central nervous system in an HIV patient: diagnostic and therapeutic challenges. [PDF]

BMC Infect Dis
Majeed I, Hannan KS, Buckley A, Khan ZR, Rasheed F, Hanbali L, Hattab EM.   +6 more
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Live attenuated varicella vaccines in patients treated with tumor necrosis factor-alpha inhibitors: A clinical trial. [PDF]

Medicine (Baltimore)
Kamei K, Ogura M, Takeuchi I, Shimizu H, Arai K, Shoji K, Kawai T, Miyairi I, Murashima A, Ogimi C.   +9 more
europepmc   +1 more source

IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α

Animal Models and Experimental Medicine, EarlyView.
IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α. Abstract Background The purpose is to define the contribution of the interferon regulatory factor‐1–dual‐specificity tyrosine phosphorylation‐regulated kinase 1α (IRF‐1–DYRK1α) axis to hepatocellular ferroptosis during liver ischemia/reperfusion injury ...
Jinping Zhang, Jinming Zhang, Siyuan Song, Mingyang Li, Liying Sun, Zhijun Zhu, Dongdong Lin   +6 more
wiley   +1 more source

Tailoring virus-inspired nanoparticles for advanced drug and gene delivery. [PDF]

Mater Today Bio
Zhou R, Xu M, Zheng X, Xu J, Li J, Tong H, Zhao C, Han J, Luo L, Li H.   +9 more
europepmc   +1 more source

Efficacy of Immune Checkpoint Inhibitors and Oncoviruses in Solid Tumors. [PDF]

Clin Cancer Res
Mechahougui H, Royston L, Vieira Gomes C, Kaiser L, Koessler T, Olivier T, Mach N, Labidi-Galy SI, Parikh K, Addeo A.   +9 more
europepmc   +1 more source

Long-term outcomes after knee endoprosthesis for a rare HIV-associated proximal tibial osteosarcoma: 15-year follow-up. [PDF]

Radiol Case Rep
Abdulraqeb S, Hua G, Zhang W, Tu C, Duan H.   +4 more
europepmc   +1 more source