Results 281 to 290 of about 1,122,815 (355)

Clinical Significance of MYBL2 Expression in Hepatocellular Carcinoma: Impact on Overall Survival. [PDF]

Onco Targets Ther
Chen CC, Wei CT, Hsuan CF, Yu TH, Hung WC, Wu CC, Lee TL, Tang WH, Chung FM, Lee YJ, Hsu CC.   +10 more
europepmc   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

​​The immune microenvironment of pathogen-associated cancers and current clinical therapeutics. [PDF]

Mol Cancer
Wei XY, Feng HJ, Zhu YY, Guo SJ, Wang H, Li M, Mei Q.   +6 more
europepmc   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Cellular Senescence as a Risk Factor in Head and Neck Cancer-Diagnostic and Therapeutic Perspective. [PDF]

Cancers (Basel)
Stachowiak M, Kostrzewa M, Golusinski W, Golusinski P, Golusinska-Kardach E, Masternak MM, Rubiś B.   +6 more
europepmc   +1 more source

An Autochthonous Model of Lung Cancer Identifies Requirements for Cellular Transformation in the Naked Mole Rat. [PDF]

Cancer Discov
Shepard A, Lester DK, Troutman S, Hoxha S, Khaled WT, Smith ESJ, Park TJ, Buffenstein R, Du D, Teng M, Dengler-Crish CM, Tsai KY, Flores ER, Ventura A, Kissil JL.   +14 more
europepmc   +1 more source

HIV, Viral Hepatitis, and Schistosomiasis Association with Liver Cancer: A Systematic Review. [PDF]

Microorganisms
Canham K, Naidoo P, Senzani S, Kader SS, Mkhize-Kwitshana ZL.   +4 more
europepmc   +1 more source

Recent perspectives on macrophage memory: types, mechanisms, and characteristics in pulmonary diseases. [PDF]

Cell Commun Signal
Wang S, Wang B, Qiu Y, Lu Y, Gu H, Wang B, Wang J.   +6 more
europepmc   +1 more source