Results 11 to 20 of about 66,124 (248)
Frontiers in Oncology, 2022 miRNAs play a crucial role in regulating genes involved in cancer progression. Recently, miR-153 has been mainly well-known as a tumor suppressive miRNA modulating genes in proliferation, metastasis, EMT, angiogenesis and drug resistance ability of a ...
Saghar Yousefnia
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Anti-HERV-K Drugs and Vaccines, Possible Therapies against Tumors
Vaccines, 2023 The footprint of human endogenous retroviruses (HERV), specifically HERV-K, has been found in malignancies, such as melanoma, teratocarcinoma, osteosarcoma, breast cancer, lymphoma, and ovary and prostate cancers.
Sepideh Hosseiniporgham +1 more
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The Tropomyosin Family as Novel Biomarkers in Relation to Poor Prognosis in Glioma
Biology, 2022 (1) Background: The functions of the tropomyosin (TPM) family in tumors and cancers have been explored; however, striking differences have been observed.
Ke Huang +6 more
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Vortioxetine induces apoptosis and autophagy of gastric cancer AGS cells via the PI3K/AKT pathway
FEBS Open Bio, 2020 Vortioxetine is a potent antagonist of the 5‐hydroxytryptamine receptor and serotonin transporter and has been reported to function as an antidepressant in the treatment of major depressive disorder. However, its antitumor effects remain unclear.
Gao‐Bo Lv +5 more
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Knockout of ENO1 leads to metabolism reprogramming and tumor retardation in pancreatic cancer
Frontiers in Oncology, 2023 The shift in glucose utilization from oxidative phosphorylation to glycolysis is the hallmark of tumor cells. The overexpression of ENO1, one of the key enzymes in the glycolysis process, has been identified in several cancers, however, its role in ...
Qingru Song +5 more
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An anti-cancer surveillance by the interplay between interferon-beta and retinoblastoma protein RB1
Frontiers in Oncology, 2023 Interferon-beta (IFN-β), an extracellular cytokine that initiates signaling pathways for gene regulation, has been demonstrated to function as a tumor suppressor protein through lentiviral gene transduction.
Albert Qin
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Frontiers in Oncology, 2021 ObjectiveTo investigate the effects of NK4 gene on the properties and tumorigenicity in laryngeal squamous cell carcinoma cell.MethodsHere, we used the attenuated Salmonella carrying the NK4 gene to transfect the AMC-HN-8 cells and detected the ...
Shoukai Zhang +6 more
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Glioma, 2019 Background and Aim: Mechanisms of glioma progression are poorly understood. Upregulation of calcium-activated potassium channel subunit alpha-1 (KCNMA1), which encodes the α-subunit of maxi-calcium-activated potassium (BKCa) channels, is shown to be a ...
Divya Khaitan, Nagendra Ningaraj
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Biomedicines, 2022 Cell therapy products have significant limitations, such as storage instability, difficulties with transportation, and toxicity issues such as tumorigenicity and immunogenicity.
Min Heui Yoo, A-Ram Lee, Kyoung-Sik Moon
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Stem Cell Reports, 2017 The ability to form teratomas in vivo containing multiple somatic cell types is regarded as functional evidence of pluripotency for human pluripotent stem cells (hPSCs).
Marga J. Bouma +5 more
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