Results 21 to 30 of about 13,396 (145)
Frontiers in Oncology, 2021 ObjectiveTo investigate the effects of NK4 gene on the properties and tumorigenicity in laryngeal squamous cell carcinoma cell.MethodsHere, we used the attenuated Salmonella carrying the NK4 gene to transfect the AMC-HN-8 cells and detected the ...
Shoukai Zhang +6 more
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Biomedicines, 2022 Cell therapy products have significant limitations, such as storage instability, difficulties with transportation, and toxicity issues such as tumorigenicity and immunogenicity.
Min Heui Yoo, A-Ram Lee, Kyoung-Sik Moon
doaj +1 more source
Stem Cell Reports, 2017 The ability to form teratomas in vivo containing multiple somatic cell types is regarded as functional evidence of pluripotency for human pluripotent stem cells (hPSCs).
Marga J. Bouma +5 more
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Rapamycin Response in Tumorigenic and Non-Tumorigenic Hepatic Cell Lines
PLoS ONE, 2009 The mTOR inhibitor rapamycin has anti-tumor activity across a variety of human cancers, including hepatocellular carcinoma. However, resistance to its growth inhibitory effects is common. We hypothesized that hepatic cell lines with varying rapamycin responsiveness would show common characteristics accounting for resistance to the drug.We profiled a ...
Jimenez RH +6 more
openaire +4 more sources
ONCORNAVIRUS-TRANSFORMED MARMOSET CELLS: PROPERTIES IN VITRO, TUMORIGENICITY AND IMMUNOGENICITY.
, 1975 ONCORNAVIRUS-TRANSFORMED MARMOSET CELLS: PROPERTIES IN VITRO, TUMORIGENICITY AND ...
RICHARD JAMES. MASSEY (7992890)
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KLK3 in the Regulation of Angiogenesis—Tumorigenic or Not? [PDF]
International Journal of Molecular Sciences, 2021 In this focused review, we address the role of the kallikrein-related peptidase 3 (KLK3), also known as prostate-specific antigen (PSA), in the regulation of angiogenesis. Early studies suggest that KLK3 is able to inhibit angiogenic processes, which is most likely dependent on its proteolytic activity.
Hannu Koistinen +2 more
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Molecular Therapy: Methods & Clinical Development, 2017 Human pluripotent stem cells (hPSCs) are a promising source of regenerative material for clinical applications. However, hPSC transplant therapies pose the risk of teratoma formation and malignant transformation of undifferentiated remnants.
Kaoru Mitsui +3 more
doaj +1 more source
Research progress of tumorigenicity-related proteins [PDF]
, 2020 The occurrence and development of tumors include the tumorigenicity of tumor cells in vivo, the growth of xenograft tumors, angiogenesis, tumor migration, invasion and metastasis.
AO Hui-juan, SHI Jia-chen, WANG Jia-min, Ayimuguli ABUDUREYIMU, QIAO Zi-lin, YANG Kun
core
Molecules, 2017 The use of human pluripotent stem cells (hPSCs) such as human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) in regenerative medicine is hindered by their tumorigenic potential.
Hiroaki Tateno +2 more
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Pharmaceuticals, 2021 Mesenchymal-stem/stromal-cell-derived small extracellular vesicles (MSC-sEV) have been shown to ameliorate many diseases in preclinical studies. However, translating MSC-sEV into clinical use requires the development of scalable manufacturing processes ...
Thong Teck Tan +5 more
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