Results 11 to 20 of about 13,396 (145)

Supplemental material - Tumorigenicity Assessment of Human Cancer Cell Lines Xenografted on Immunodeficient Mice as Positive Controls of Tumorigenicity Testing

open access: yes, 2022
Supplemental material for Tumorigenicity Assessment of Human Cancer Cell Lines Xenografted on Immunodeficient Mice as Positive Controls of Tumorigenicity Testing by Seunghee Oh, Eun-Young Gu, Ji-Seok Han, Byoung-Seok Lee, Kyoung-Sik Moon, Yong-Bum Kim ...
Kang-Hyun Han (205004)   +6 more
core   +19 more sources

Plasticity and Tumorigenicity [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2012
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 France Licence.
Campos-Sánchez, Elena   +2 more
openaire   +4 more sources

Anti-HERV-K Drugs and Vaccines, Possible Therapies against Tumors

open access: yesVaccines, 2023
The footprint of human endogenous retroviruses (HERV), specifically HERV-K, has been found in malignancies, such as melanoma, teratocarcinoma, osteosarcoma, breast cancer, lymphoma, and ovary and prostate cancers.
Sepideh Hosseiniporgham   +1 more
doaj   +1 more source

Vortioxetine induces apoptosis and autophagy of gastric cancer AGS cells via the PI3K/AKT pathway

open access: yesFEBS Open Bio, 2020
Vortioxetine is a potent antagonist of the 5‐hydroxytryptamine receptor and serotonin transporter and has been reported to function as an antidepressant in the treatment of major depressive disorder. However, its antitumor effects remain unclear.
Gao‐Bo Lv   +5 more
doaj   +1 more source

The Tropomyosin Family as Novel Biomarkers in Relation to Poor Prognosis in Glioma

open access: yesBiology, 2022
(1) Background: The functions of the tropomyosin (TPM) family in tumors and cancers have been explored; however, striking differences have been observed.
Ke Huang   +6 more
doaj   +1 more source

Tumorigenicity-associated characteristics of human iPS cell lines [PDF]

open access: yes, 2018
Human induced pluripotent stem cells (hiPSCs) represent promising raw materials of human cell-based therapeutic products (hCTPs). As undifferentiated hiPSCs exhibit intrinsic tumorigenicity properties that enable them to form teratomas, hCTPs containing ...
Hideki Tsutsumi (197290)   +25 more
core   +1 more source

Knockout of ENO1 leads to metabolism reprogramming and tumor retardation in pancreatic cancer

open access: yesFrontiers in Oncology, 2023
The shift in glucose utilization from oxidative phosphorylation to glycolysis is the hallmark of tumor cells. The overexpression of ENO1, one of the key enzymes in the glycolysis process, has been identified in several cancers, however, its role in ...
Qingru Song   +5 more
doaj   +1 more source

Tumorigenicity of EBNA2‐transfected cells [PDF]

open access: yesFEBS Letters, 1995
The Epstein‐Barr virus nuclear antigen 2 (EBNA2) gene is thought to be important for transformation by Epstein‐Barr virus (EBV), but the mechanism of this transformation is little understood. Here, to examine the transforming ability of EBNA2, we transfected a rat fibroblast cell line F2408 with a recombinant EBNA2 expression plasmid and examined cell ...
M, Shimakage   +5 more
openaire   +2 more sources

An anti-cancer surveillance by the interplay between interferon-beta and retinoblastoma protein RB1

open access: yesFrontiers in Oncology, 2023
Interferon-beta (IFN-β), an extracellular cytokine that initiates signaling pathways for gene regulation, has been demonstrated to function as a tumor suppressor protein through lentiviral gene transduction.
Albert Qin
doaj   +1 more source

Evidence of calcium-activated potassium channel subunit alpha-1 as a key promoter of glioma growth and tumorigenicity

open access: yesGlioma, 2019
Background and Aim: Mechanisms of glioma progression are poorly understood. Upregulation of calcium-activated potassium channel subunit alpha-1 (KCNMA1), which encodes the α-subunit of maxi-calcium-activated potassium (BKCa) channels, is shown to be a ...
Divya Khaitan, Nagendra Ningaraj
doaj   +1 more source

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