Results 31 to 40 of about 13,396 (145)
Frontiers in Cell and Developmental Biology, 2021 Our studies have demonstrated that cell tumorigenicity and pluripotent differentiation potential stem from neural stemness or a neural ground state, which is defined by a regulatory network of higher levels of machineries for basic cell physiological ...
Xiaoli Yang +16 more
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Cancer Stem Cell Functions in Hepatocellular Carcinoma and Comprehensive Therapeutic Strategies
Cells, 2020 Hepatocellular carcinoma (HCC) is a significant cause of cancer-related mortality owing to resistance to traditional treatments and tumor recurrence after therapy, which leads to poor therapeutic outcomes.
Yu-Chin Liu +2 more
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EphA2 as a promoter of melanoma tumorigenicity [PDF]
Cancer Biology & Therapy, 2009 The greatest health threat from malignant melanoma is death due to metastatic disease. Consequently, the identification of markers predictive of metastatic disease is essential for identifying new therapeutic targets. EphA2, a protein tyrosine kinase receptor commonly expressed in epithelial cells, has been found to be overexpressed and constitutively ...
Naira V, Margaryan +6 more
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Cancer Management and Research, 2020 Feng Rong, Liang Liu, Can Zou, Jing Zeng, Yasheng Xu Department of Respiratory, Xiantao First People’s Hospital Affiliated to Changjiang University, Xiantao, Hubei, People’s Republic of ChinaCorrespondence: Yasheng Xu Tel +86 728-3220705Email
Rong F, Liu L, Zou C, Zeng J, Xu Y
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The prognostic role and metabolic function of GGPS1 in oral squamous cell carcinoma
Frontiers in Molecular Biosciences, 2023 Background: GGPS1(geranylgeranyl diphosphate synthase 1) is a member of the prenyltransferase family. Abnormal expression of GGPS1 can disrupt the balance between protein farnesylation and geranylgeranylation, thereby affecting a variety of cellular ...
Ke Huang +7 more
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Tumorigenicity Assay in Nude Mice [PDF]
BIO-PROTOCOL, 2017 Tumorigenicity refers to the ability of cultured cells to develop viable tumors in immune-deficient animals. The goal of this protocol is to illustrate tumorigenicity assay by subcutaneous tumor-cell-transplantation in nude mice. Target cells are transplanted to 6-week-old nude mice subcutaneously and the tumor growth is monitored over a period of ...
Feng Du, Xiaodi Zhao, Daiming Fan
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Cell line quality and tumorigenicity parameters.
, 2017 Cell line quality and tumorigenicity parameters.
Tina Lombardo (3612701) +7 more
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Novel miR-5088-5p promotes malignancy of breast cancer by inhibiting DBC2
Molecular Therapy: Nucleic Acids, 2021 Breast cancer is the most common female cancer in the world. Despite the active research on metastatic breast cancer, the treatment of breast cancer patients is still difficult because the mechanism is not well known.
Hyun Jeong Seok +7 more
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Tumorigenic and adhesive properties of heparanase [PDF]
Seminars in Cancer Biology, 2010 Heparanase is an endo-β-glucuronidase that cleaves heparan sulfate side chains presumably at sites of low sulfation, activity that is strongly implicated with cell invasion associated with cancer metastasis, a consequence of structural modification that loosens the extracellular matrix barrier.
Flonia, Levy-Adam +2 more
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Tumorigenicity assays in nude mice.
, 2012 (A). Tumorigenicity assays for astrocytes. Tumor formation could not be detected either in the unexposed group or in exposed groups (B). Tumorigenicity assays for C6 cells and HE staining of tumors.
An-ming Li (146911) +10 more
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