Results 51 to 60 of about 13,396 (145)

A Unique Model System for Tumor Progression in GBM Comprising Two Developed Human Neuro-Epithelial Cell Lines with Differential Transforming Potential and Coexpressing Neuronal and Glial Markers

open access: yesNeoplasia: An International Journal for Oncology Research, 2003
The molecular mechanisms involved in tumor progression from a low-grade astrocytoma to the most malignant glioblastoma multiforme (GBM) have been hampered due to lack of suitable experimental models.
Anjali Shiras   +6 more
doaj   +1 more source

Correlation of in vitro growth properties and tumorigenicity of Syrian hamster cell lines [PDF]

open access: yes, 1979
Several in vitro phenotypic characteristics frequently associated with neoplastic cells were examined in a series of spontaneous and benzo(a)pyrene-induced Syrian hamster clonal cell lines which differed in their degree of tumorigenicity.
Ts'o, P. O.   +5 more
core   +1 more source

Morphine Suppresses Liver Cancer Cell Tumor Properties In Vitro and In Vivo

open access: yesFrontiers in Oncology, 2021
Morphine is an analgesic widely adopted to relieve cancer pain. A number of discrepancies, however, are presented by the published literature, with reports suggesting that opioids may either promote or inhibit the spread of cancer.
Hao-Wen Zhang   +5 more
doaj   +1 more source

Propagation and Maintenance of Cancer Stem Cells: A Major Influence of the Long Non-Coding RNA H19

open access: yesCells, 2020
Cancer stem cells (CSCs) represent a rare population of tumor cells that exhibit stem cell properties with the abilities of self-renewal and differentiation.
Clément Lecerf   +3 more
doaj   +1 more source

Flavopereirine Suppresses the Progression of Human Oral Cancer by Inhibiting the JAK-STAT Signaling Pathway via Targeting LASP1

open access: yesDrug Design, Development and Therapy, 2021
Junwu Xu, Zhiyuan Wu, Jian Huang Department of Oral and Maxillofacial Surgery, Fujian Provincial Hospital, Fuzhou City, Fujian Province, 350001, People’s Republic of ChinaCorrespondence: Junwu Xu Tel + 86-591-87557768Email junwuxufujian@163 ...
Xu J, Wu Z, Huang J
doaj  

Animal models of tumorigenic herpesviruses — an update [PDF]

open access: yesCurrent Opinion in Virology, 2015
Any one model system, be it culture or animal, only recapitulates one aspect of the viral life cycle in the human host. By providing recent examples of animal models for Epstein Barr Virus and Kaposi Sarcoma-associated Herpesvirus, we would argue that multiple animal models are needed to gain a comprehensive understanding of the pathogenesis associated
Dirk P, Dittmer   +2 more
openaire   +2 more sources

Differential Gene Expression and Tumorigenicity Analysis of Cultured Melanocyte Comparing Melanoma [PDF]

open access: yesInternational Journal of Molecular and Cellular Medicine
This study aimed to identify the optimal growth media for culturing human skin melanocytes for clinical applications and to assess their tumorigenic potential both in vitro and in vivo. Various growth media were tested to determine the most effective and
Atefeh Shahbazi   +4 more
doaj  

RETRACTED: Long Non-coding RNA LINC00320 Inhibits Tumorigenicity of Glioma Cells and Angiogenesis Through Downregulation of NFKB1-Mediated AQP9

open access: yesFrontiers in Cellular Neuroscience, 2020
The inhibitory effect of long intergenic non-coding RNA 00320 (LINC00320) in glioma cell proliferation has been proposed in a recent study. However, the mechanisms by which LINC00320 regulate aquaporin 9 (AQP9) in glioma require further exploration ...
Lisha Chang   +7 more
doaj   +1 more source

Comparison of Clinical Features and Outcomes in Epithelial Ovarian Cancer according to Tumorigenicity in Patient-Derived Xenograft Models [PDF]

open access: yes, 2018
Purpose: Although the use of xenograft models is increasing, few studies have compared the clinical features or outcomes of epithelial ovarian cancer (EOC) patients according to the tumorigenicity of engrafted specimens.
어경진   +10 more
core   +1 more source

Human Metastatic Melanoma Cell Lines Panel for In Vitro and In Vivo Investigations

open access: yesJournal of Molecular Pathology
The melanoma origin of cell lines obtained from the axillary lymph node (mel Kas, mel Pet, and mel Lap from patients with a verified diagnosis) was confirmed by the detection of the Melan A melanocyte marker expression.
Ekaterina N. Kosobokova   +15 more
doaj   +1 more source

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