Role of tunneling nanotubes in neuroglia [PDF]
Neural Regeneration ResearchTunneling nanotubes are crucial structures for cellular communication and are observed in a variety of cell types. Glial cells, the most abundant cells in the nervous system, play a vital role in intercellular signaling and can show abnormal activation ...
Weichen Xu +4 more
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Tunneling Nanotubes Facilitate Intercellular Protein Transfer and Cell Networks Function [PDF]
Frontiers in Cell and Developmental Biology, 2022 The past decade witnessed a huge interest in the communication machinery called tunneling nanotubes (TNTs) which is a novel, contact-dependent type of intercellular protein transfer (IPT).
Laura Turos-Korgul +4 more
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Melatonin, tunneling nanotubes, mesenchymal cells, and tissue regeneration [PDF]
Neural Regeneration Research, 2023 Mesenchymal stem cells are multipotent stem cells that reside in many human tissues and organs. Mesenchymal stem cells are widely used in experimental and clinical regenerative medicine due to their capability to transdifferentiate into various lineages.
Francesca Luchetti +4 more
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Chlamydia trachomatis Cell-to-Cell Spread through Tunneling Nanotubes [PDF]
Microbiology Spectrum, 2022 Tunneling nanotubes (TNTs) are transient cellular connections that consist of dynamic membrane protrusions. They play an important role in cell-to-cell communication and mediate the intercellular exchanges of molecules and organelles.
Rico Jahnke +4 more
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A role for tunneling nanotubes in virus spread [PDF]
Frontiers in MicrobiologyTunneling nanotubes (TNTs) are actin-rich intercellular conduits that mediate distant cell-to-cell communication and enable the transfer of various cargos, including proteins, organelles, and virions.
Weimiao Lv +9 more
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Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators [PDF]
eLifeTunneling nanotubes (TNTs) are open actin- and membrane-based channels, connecting remote cells and allowing direct transfer of cellular material (e.g. vesicles, mRNAs, protein aggregates) from the cytoplasm to the cytoplasm.
Roberto Notario Manzano +6 more
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Tunneling nanotubes provide a new route for bovine viral diarrhea virus spreading [PDF]
Frontiers in Veterinary ScienceIntroductionBovine viral diarrhea virus (BVDV) is one of the major pathogens currently endangering the world's cattle industry. It poses serious difficulties in prevention and treatment because it can infect cattle of all ages and the specific mechanism ...
Jiying Yin +14 more
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Mechanical properties of intercellular tunneling nanotubes formed by different mechanisms [PDF]
HeliyonTunneling nanotubes (TNTs) that connect cells have been recognized as a pathway for long-range intercellular transport of diverse cargoes, including viruses, lysosomes or other organelles, Ca2+ and electrical signals.
Yanli Sun +4 more
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Interplay between tunneling nanotubes and Wnt Signaling: Insights into cytoskeletal regulation and therapeutic potential [PDF]
Biochemistry and Biophysics ReportsTunneling nanotubes (TNTs) are membranous structures that enable direct intercellular transfer of mitochondria, proteins, RNAs, and signaling molecules, playing key roles in tissue repair, immune coordination, and stress adaptation.
Tengfei Feng +4 more
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Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma. [PDF]
PLoS ONE, 2012 Tunneling nanotubes are long, non-adherent F-actin-based cytoplasmic extensions which connect proximal or distant cells and facilitate intercellular transfer.
Emil Lou +9 more
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