Results 61 to 70 of about 142 (121)

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

Brain Pathology, Volume 36, Issue 4, July 2026.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña, Enric Vidal, Natalia Fernández‐Borges, Jorge M. Charco, Carlos M. Díaz‐Domínguez, Cristina Sampedro‐Torres‐Quevedo, Josu Galarza‐Ahumada, Eva Fernández‐Muñoz, Maitena San‐Juan‐Ansoleaga, Miguel Ángel Pérez‐Castro, Nuno Gonçalves‐Anjo, Patricia Piñeiro, Samanta Giler, Nora González‐Martín, Nuria L. Lorenzo, Africa Manero‐Azua, Guiomar Perez de Nanclares, Mariví Geijo, Manuel A. Sánchez‐Martín, Jesús R. Requena, Joaquín Castilla   +20 more
wiley   +1 more source

Ellipse offset curves in the formation of turbo-roundabouts

Roads and Bridges - Drogi i Mosty, 2015
Various curves are used for shaping the geometry of roads and a curve applied the most often is the circular arc. Clothoid, spiral, ellipse, sets of curves shaped with polynomial functions and other similar curves are also worth mentioning. The road axis is usually set during practical realization of the curves in the terrain.
openaire   +1 more source

On Not Being Stuck: Changing Humanities in 20th‐ and 21st‐Century Britain: The Lorna Sage Lecture, 2025

Critical Quarterly, EarlyView.
Helen Small
wiley   +1 more source

BLADE‐ON‐PETIOLE Genes Enable Genetic Bottleneck Mitigation Through Cross‐Species Repurposing of Floral Persistence Traits

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study shows that BLADE‐ON‐PETIOLE (BOP) proteins regulate floral abscission and senescence in tomato by interacting with TFAM1 to form transcriptional condensates controlling the ARABIDOPSIS THALIANA HOMEOBOX GENE 1 (ATH1)‐mediated abscission pathway.
Nan Xiao, Qianwen Lyu, Tinghao Zhang, Yupan Zou, Yue Xie, Dandan Yang, Cao Xu, Xiaozhen Huang   +7 more
wiley   +1 more source

Preparation, Component Identification, and Antioxidant Activity of Anthocyanins From Punica granatum “Tunisia”

AgriFood: Journal of Agricultural Products for Food, Volume 2, Issue 2, Page 127-140, June 2026.
The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang, Xu‐han Yang, Meng‐qi Zhang, Xu Guo, Ning‐yang Li, Fang‐yu Long, Chao Liu   +6 more
wiley   +1 more source

Turbo Roundabouts: Case Study of Croatia

, 2018
The popularity of various roundabout types has driven substantial efforts to optimize their de-sign procedures. Implementing effective roundabouts is a highly demanding task and requires op-timizing traffic (operational) efficiency (TE) and traffic safety (TS) while considering various geome-try factors and constraints. The turbo roundabout concept has
Pilko, Hrvoje, Šarić, Željko, Zovak, Goran   +2 more
openaire   +3 more sources

Evaluation of the performance of ChatGPT‐4 and ChatGPT‐4o as a learning tool in endodontics

International Endodontic Journal, Volume 59, Issue 6, Page 1057-1069, June 2026.
Abstract Aims The aim of this study was to evaluate the accuracy and consistency of responses given by two different versions of Chat Generative Pre‐trained Transformer (ChatGPT), ChatGPT‐4, and ChatGPT‐4o, to multiple‐choice questions prepared from undergraduate endodontic education topics at different times of the day and on different days ...
Esra Arılı Öztürk, Ceren Turan Gökduman, Burhan Can Çanakçi   +2 more
wiley   +1 more source

Investigating Dietary Polyphenol Intake in the Australian Population: Results From the 2011–12 National Nutrition and Physical Activity Survey

Journal of Human Nutrition and Dietetics, Volume 39, Issue 3, June 2026.
ABSTRACT Introduction There is a lack of detailed polyphenol intake data collected at the national level, both in Australia and globally. Hence, the aim of this study was to estimate the intake of total polyphenols, polyphenol classes, and polyphenol subclasses in a nationally representative sample of Australians across the lifespan. Methods Polyphenol
Elizabeth Gamage, Mohammadreza Mohebbi, Mojtaba Lotfaliany, Deborah N. Ashtree, Melissa M. Lane, Rebecca Orr, Felice N. Jacka, Wolfgang Marx   +7 more
wiley   +1 more source

Total capacity and LOS estimation of innovative and conventional roundabouts through macroscopic fundamental diagrams

Transportation Research Interdisciplinary Perspectives
Traffic congestion remains a significant problem, especially in urban areas. To avoid congestion phenomena, several measures can be adopted, including the construction of roundabouts and the control of the measures of effectiveness (MOEs) at ...
Marco Guerrieri
doaj   +1 more source

THE ELEMENTS OF THE SITUATIONAL PLAN AND LONGITUDINAL PROFILE OF TURBO ROUNDABOUTS

AGG+, 2018
<p>Turbo roundabouts are a relatively new type of roundabouts, designed to increase the capacity and safety of single-lane and double-lane roundabouts. Turbo roundabouts consist of elements that are characteristical for classic roundabouts and new elements that occur exclusively in this kind of roundabouts. In this paper the basic concept
Ljiljana Milić-Marković, Gordana Tutorić   +1 more
openaire   +1 more source