Results 51 to 60 of about 182,785 (292)

Investigations of Free Turbulent Mixing [PDF]

, 1947
A discussion of the integral relations for the flow of the boundary-layer type is presented. It is shown that the characteristic laws of spread of jets, wakes, and so forth, can be obtained directly for the laminar case and, with the help of dimensional ...
Laufer, John, Liepmann, Hans Wolfgang
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

CFD study of the PTS experiment in ROCOM test facility

Nuclear Engineering and Technology, 2020
With the aging of nuclear reactors, embrittlement of the reactor pressure vessel (RPV) steel, as a consequence of routine operations, is highly probable.
Zoran Čarija, Fran Ledić, Ante Sikirica, Bojan Niceno   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Effects of turbulent mixing on critical behaviour in the presence of compressibility: Renormalization group analysis of two models

, 2010
Critical behaviour of two systems, subjected to the turbulent mixing, is studied by means of the field theoretic renormalization group. The first system, described by the equilibrium model A, corresponds to relaxational dynamics of a non-conserved order ...
A S Kapustin, Antonov N V, Antonov N V, Antonov N V, Antonov N V, Antonov N V Ignatieva A A Malyshev A V, Folk R, Honkonen J, Ivanov D Yu, Janssen H-K, Khmel'nitski D E, N V Antonov, Shalaev B N, van Kampen N G, Zinn-Justin J   +14 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Numerical study of turbulent flow under different flow mixing devices in a scaled-down reactor pressure vessel model

Nuclear Engineering and Technology
Turbulent flow in reactor pressure vessel (RPV) of pressurized water reactor (PWR) is complicated because the complex geometry in RPV. The flow rates through fuel assemblies at core inlet are strongly influenced by different designs of flow mixing ...
Wenhai Qu, Hao Xie, Chong Chen, Hanyu Wang, Danhong Shen, Qi Lu, Jian Deng   +6 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Turbulent Mixing in Clusters of Galaxies

, 2003
We present a spherically-symmetric, steady-state model of galaxy clusters in which radiative cooling from the hot gas is balanced by heat transport through turbulent mixing. We assume that the gas is in hydrostatic equilibrium, and describe the turbulent
Brighenti F., Churazov E., Deiss B. M., Ramesh Narayan, Valageas P., White D. A., Woong-Tae Kim   +6 more
core   +1 more source