Results 71 to 80 of about 5,905 (264)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Transport and mixing by finite-size particles in turbulent flows

, 2022
   Suspensions of solid particles in a viscous fluid are ubiquitous in natural and engineering settings, including sediment transport in river beds, blood flow in the human body, oil products transport in pipelines and pulp fibers in papermaking.     Multiphase flows consisting of finite-size particles is a challenging topic due to multi-way coupling ...
openaire   +1 more source

Multi‐Scale Physical Modulation of Surface‐Layer Wind Profile and Momentum Flux in the Peripheral Circulation of Super Typhoon Yagi

Geophysical Research Letters
This study presents analysis of the nearshore marine atmospheric surface layer during Super Typhoon Yagi using detailed observational data. As the typhoon's peripheral circulation intensified, wind speeds increased across the observed heights (16.4–35.1 ...
Jing Liang, Lei Li, Pak Wai Chan, Qianjin Zhou, Ling Huang, Sheng Hu   +5 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

RANS Modeling of Stably Stratified Turbulent Boundary Layer Flows in OpenFOAM®

E3S Web of Conferences, 2015
Quantifying mixing processes relating to the transport of heat, momentum, and scalar quantities of stably stratified turbulent geophysical flows remains a substantial task. In a stably stratified flow, such as the stable atmospheric boundary layer (SABL),
Wilson Jordan M., Venayagamoorthy Subhas K.   +1 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Numerical and experimental investigation of turbulence and transport in mixing geometries

, 2018
Turbulent mixing processes in three different flow configurations are studied using a combination of experimental data and computational fluid dynamics. The turbulent transport of a passive scalar in a wake and jet with co-flow in a rectangular reactor is studied using large eddy simulation and experimental data from particle image velocimetry (PIV ...
openaire   +3 more sources

Evolution of confined mixing layer under optimal excitation frequency [PDF]

International Journal of Fluid Engineering
The exceptionally rapid fluid mixing that is achievable in confined mixing layers through external excitation is studied through both flow visualization and particle image velocimetry at a moderate Reynolds number.
Wei Zhao, Guiren Wang
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

ATOMIX benchmark datasets for dissipation rate measurements using shear probes

Scientific Data
Turbulent mixing in the ocean, lakes and reservoirs facilitates the transport of momentum, heat, nutrients, and other passive tracers. Turbulent fluxes are proportional to the rate of turbulent kinetic energy dissipation per unit mass, ε. A common method
Ilker Fer, Marcus Dengler, Peter Holtermann, Arnaud Le Boyer, Rolf Lueck   +4 more
doaj   +1 more source