Results 51 to 60 of about 2,462,893 (295)

Ultra long turbulent eddies, magnetic topology, and the triggering of internal transport barriers in tokamaks

open access: yesNuclear Fusion, 2022
Local nonlinear gyrokinetic simulations of tokamak plasmas demonstrate that turbulent eddies can extend along magnetic field lines for hundreds of poloidal turns when the magnetic shear is very small.
Arnas Volčokas   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hierarchy of turbulent transport models with the SOLEDGE3X code

open access: yesNuclear Fusion
Efficient and fast predictive simulations of turbulent transport in the tokamak edge plasma remain a challenge and are key for preparing the operation and heat exhaust on fusion power plants.
H. Bufferand   +19 more
doaj   +1 more source

Transport and modeling of subgrid-scale turbulent kinetic energy in channel flows

open access: yesAIP Advances, 2022
To develop a more convenient subgrid-scale (SGS) model that performs well even in coarse grid cases, we investigate the transport and modeling of SGS turbulent kinetic energy (hereafter SGS energy) in turbulent channel flows based on the stabilized mixed
Kazuhiro Inagaki, Hiromichi Kobayashi
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A Statistical Dynamic Model for the Turbulent Transport of Kinetic Energy in Shear Layers

open access: yesJournal of Aerospace Technology and Management, 2018
Dynamic statistical equations for the turbulent fluxes of scalars and momentum in incompressible flows are derived after time wise integration of the equation for the oscillating transported property, decomposing the turbulent fluxes in terms ...
José Ricardo Figueiredo
doaj  

Comparable levels of turbulent and neoclassical transport of high-Z impurities: integrated modelling in AUG, JET and C-Mod

open access: yesNuclear Fusion
Operation with beam heating is prone to central accumulation of high- Z impurities in present-day tokamaks due to a dominant neoclassical pinch. Fusion reactors are expected to have a different core transport regime for high- Z impurities, where ...
D. Fajardo   +19 more
doaj   +1 more source

A numerical analysis of pollutant dispersion in street canyon: influence of the turbulent Schmidt number

open access: yesPrzegląd Naukowy Inżynieria i Kształtowanie Środowiska, 2017
Realizing the growing importance and availability of motor vehicles, we observe that the main source of pollution in the street canyons comes from the dispersion of automobile engine exhaust gas.
Bouabdellah Abed   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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