Results 61 to 70 of about 2,462,893 (295)

Aircraft Wake Vortex Deformation in Turbulent Atmosphere [PDF]

open access: yes, 2007
Large-scale distortion of aircraft wake vortices appears to play a crucial role for aircraft safety during approach and landing. Vortex distortion is investigated based on large eddy simulations of wake vortex evolution in a turbulent atmosphere.
Hennemann, Ingo, Holzaepfel, Frank
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

On the observability of turbulent transport rates by Argo: supporting evidence from an inversion experiment [PDF]

open access: yesOcean Science, 2015
Although estimation of turbulent transport parameters using inverse methods is not new, there is little evaluation of the method in the literature. Here, it is shown that extended observation of the broad-scale hydrography by Argo provides a path ...
G. Forget, D. Ferreira, X. Liang
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Resonance enhanced turbulent transport [PDF]

open access: yes, 2007
The effect of oscillatory shear flows on turbulent transport of passive scalar fields is studied by numerical computations based on the results provided by E. Kim [Physics of Plasmas 13, 022308 (2006)] .
Andrew P. L. Newton   +3 more
core   +1 more source

Turbulent drifts of impurity ions as an explanation for anomalous radial transport in the far-SOL of DIII-D

open access: yesNuclear Fusion
Successful fusion reactor operation relies on minimal core contamination by impurities, otherwise too much power may be radiated and harm performance. This requires reliable predictions of impurity transport from the scrape-off layer (SOL) into the core,
S.A. Zamperini   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Mixing and Isosurface Geometry in Turbulent Transverse Jets [PDF]

open access: yes, 2001
Mixing and the geometry of jet-fluid-concentration level sets in turbulent transverse jets were experimentally studied. Jet-fluid concentration fields were measured with laser-induced fluorescence and digital imaging techniques for Reynolds numbers ...
Shan, Wei-Jen Jerry
core   +1 more source

Effect of turbulent fluctuations on neutral particles transport with the TOKAM3X-EIRENE turbulence code

open access: yesNuclear Materials and Energy, 2019
The effect of turbulent fluctuations on the transport of neutral particles (atoms, molecules) in tokamak plasmas is investigated with the 3D global turbulence code TOKAM3X-EIRENE in limiter geometry.
D.M. Fan   +6 more
doaj   +1 more source

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