Results 41 to 50 of about 511,586 (292)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Managerial competencies in tackling an acute company crisis

open access: yesAgricultural Economics (AGRICECON), 2008
The crisis manager's goal is not only to stop the crisis development in the company, but, as a further step, to achieve the fundamental turnover in its development leading to a successful solution.
R. Zuzák, P. Rymešová
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Agricultural and food wholesale and retail trade in the intra-community trade

open access: yesAgricultural Economics (AGRICECON), 2008
The paper focuses on the evaluation of the contemporary situation of two economic sectors in the frame of the European Union, namely the wholesale and retail of agricultural and food products.
M. Záboj
doaj   +1 more source

EFFECT OF CASH TURNOVER, RECEIVABLE TURNOVER, AND INVENTORY TURNOVER ON PROFITABILITY

open access: yesIndonesian Journal of Economy, Business, Entrepreneuship and Finance, 2022
The study used secondary data obtained from the web www.idx.co.id. The analysis used in this study was using multiple linear regressions used to examine the influence of independent variables on dependent variables, a study population of 182 companies and a research sample of 48 companies selected using purposive sampling techniques. The results showed
Mochamad Ihza Prasena   +2 more
openaire   +1 more source

Workplace Violence and Turnover Intention Among Psychiatrists in a National Sample in China: The Mediating Effects of Mental Health [PDF]

open access: gold, 2022
Yanhua Chen   +10 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Research of produstion volume and market turnover of honey from 2004. to 2014. [PDF]

open access: yesVeterinarski Glasnik, 2015
The objective of this work was to investigate the scope of production, export and import of honey in the Republic of Serbia from 2004. to 2014. The results are based on the report of the Statistical Office of the Republic of Serbia. The observed
Ivanović Jelena   +6 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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