Results 61 to 70 of about 1,535,051 (285)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Upregulated liver conversion of α-linolenic acid to docosahexaenoic acid in rats on a 15 week n-3 PUFA-deficient diets⃞

open access: yesJournal of Lipid Research, 2007
We quantified incorporation rates of plasma-derived α-linolenic acid (α-LNA, 18:3n-3) into “stable” liver lipids and the conversion rate of α-LNA to docosahexaenoic acid (DHA, 22:6n-3) in male rats fed, after weaning, an n-3 PUFA-adequate diet (4.6% α ...
Miki Igarashi   +5 more
doaj   +1 more source

CEO replacement under private information [PDF]

open access: yes, 2009
We study a model of “information-based entrenchment” in which the CEO has private information that the board needs to make an efficient replacement decision. Eliciting the CEO’s private information is costly, as it implies that the board must pay the CEO
Inderst, Roman, Müller, Holger
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Firm performance and managerial turnover: the case of Ukraine [PDF]

open access: yes, 2009
The paper studies whether and how CEO turnover in Ukrainian firms is related to their performance. Based on a novel dataset covering Ukrainian joint stock companies in 2002-2006, the paper finds statistically significant negative association between the ...
Bilyk, Ol'ga   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

FINANCIAL AND ECONOMIC INNOVATIONS AS A TOOL FOR ANTI-CRISIS FINANCIAL MANAGEMENT AT AN ENTERPRISE

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики, 2019
In the conditions of the transformational processes of the national economy, the problem of ensuring innovation activity is a special place in the issues of ensuring socio-economic development of society.
V. M. Cherba   +3 more
doaj   +1 more source

Src Regulation of Cx43 Phosphorylation and Gap Junction Turnover

open access: yesBiomolecules, 2020
The gap junction protein Connexin43 (Cx43) is highly regulated by phosphorylation at over a dozen sites by probably at least as many kinases. This Cx43 “kinome” plays an important role in gap junction assembly and turnover.
Joell L. Solan, Paul D. Lampe
doaj   +1 more source

EFFECT OF CASH TURNOVER, RECEIVABLE TURNOVER, AND INVENTORY TURNOVER ON PROFITABILITY

open access: yesIndonesian Journal of Economy, Business, Entrepreneuship and Finance, 2022
The study used secondary data obtained from the web www.idx.co.id. The analysis used in this study was using multiple linear regressions used to examine the influence of independent variables on dependent variables, a study population of 182 companies and a research sample of 48 companies selected using purposive sampling techniques. The results showed
Mochamad Ihza Prasena   +2 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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