Results 81 to 90 of about 979,323 (357)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Relating Employee Satisfaction and Voluntary Turnover [PDF]
Voluntary turnover has been an enduring topic in organizational management theory and a subject of numerous empirical studies due to its great influence on organizations’ efficiency.
Janika SILLAMAE
core
Analyzing employee attrition of research and development firms using mixed methods
Cogent Business & ManagementEmployees are the assets of an organization as they are the source of an indispensable and sustainable competitive advantage. Employee attrition is critical to the knowledge-intensive Research and Development (R&D) industry due to information loss.
Govind Nath Srivastava +3 more
doaj +1 more source
The trouble with teacher turnover: How teacher attrition affects students and schools
Education Policy Analysis Archives, 2019 Addressing teacher turnover is critical to stemming the country's continuing teacher shortages. It is also important for school effectiveness, as the academic and financial costs of teacher turnover to student learning and district budgets are ...
Desiree Carver-Thomas +1 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Turnover Processes in a Temporal Context: It's About Time [PDF]
To better understand the process of organizational withdrawal, a turnover model incorporating dynamic predictors measured at five distinct points in time was examined by following a large, occupationally diverse sample over a two-year period.
Theresa M. Glomb +3 more
core
, 2014 This study examined the extent to which changes over time in clinicians’ responses to measures of work attitude (eg, job satisfaction) and psychological climate (eg, supervisor support) could predict actual turnover and turnover intentions above and ...
Bryan R. Garner, Brooke D. Hunter
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
How Teacher Turnover Harms Student Achievement [PDF]
Researchers and policymakers often assume that teacher turnover harms student achievement, but recent evidence calls into question this assumption. Using a unique identification strategy that employs grade-level turnover and two classes of fixed-effects ...
James Wyckoff +3 more
core
BMC Health Services Research, 2019 BackgroundBurnout and employee turnover in mental health services are costly and can have a negative impact on service user outcomes. Using the Job Demands-Resources model as a foundation, the aim of this study was to explore the relationships between ...
J. Scanlan, M. Still
semanticscholar +1 more source