Results 101 to 110 of about 983,096 (374)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

PENGARUH STRES KERJA DAN KOMITMEN ORGANISASI TERHADAP TURNOVER INTENTION KARYAWAN PT. LION SUPERINDO , TANGERANG [PDF]

, 2015
Annisa Rahmiany Fitri, 2016; The Influence of Job Stress and Organizational Commitment On Turnover Intention Of Employees PT. Lion Superindo, Tangerang.
FITRI, ANNISA RAHMIANY
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Mediating Effects of Burnout in the Association Between Emotional Labor and Turnover Intention in Korean Clinical Nurses

Safety and Health at Work, 2020
Background: The current lack of the number of nurses and high nurse turnover rate leads to major problems for the health-care system in terms of cost, patient care ability, and quality of care.
Chi-Yun Back, Dae-Sung Hyun, Da-Yee Jeung, Sei-Jin Chang   +3 more
doaj   +1 more source

ANALISIS PENGARUH KOMPENSASI, KOMITMEN ORGANISASIONAL, DAN KEPEMIMPINAN TERHADAP TURNOVER INTENTION (Studi Pada Perusahaan X) [PDF]

, 2016
Turnover intentions is common term we hear every day, especially in X Company. The occurrence of turnover intention phenomenon is influenced by some factors such as compensation, organizational commitment, and leadership.
NUGRAHENI , Rini, PUSPASARI, Orchita
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Peran Leader-Member Exchange (LMX) dan Occupational Stress untuk Memprediksi Intensi Turnover

Gadjah Mada Journal of Psychology, 2019
The aim of this study was to examine the effect of leader-member exchange (LMX) and occupational stress on the turnover intention on PT. Komatsu Indonesia’s employees.
Ramadhan Ulfah Widyaningsih, Ridwan Saptoto   +1 more
doaj   +1 more source

Personal characteristics, occupational stress and turnover intentions among school teachers in Negeri Sembilan, Malaysia [PDF]

, 2007
Stress is considered as a serious problem in the modern workplace. This paper summarizes occupational stress and turnover intentions experienced by secondary school teachers in the state of Negeri Sembilan, Malaysia.
Abdullah, Muhammad Madi, Hitam, Sabihah, Idrus, Durrishah, Salahudin, Shahrul Nizam   +3 more
core  

PENGARUH STRESS KERJA TERHADAP TURNOVER INTENTION KARYAWAN DIMEDIASI OLEH KEPUASAN KERJA (Studi Kasus Pada J&T Express Kota Malang) [PDF]

, 2023
The many phenomena that occur on social media related to expedition employees experiencing problems at work have given rise to allegations that employees have a tendency to be susceptible to wanting to leave the company for various reasons.
Wicaksana, Thiyo
core  

Determinants of employee turnover intention

Corporate Communications: An International Journal, 2017
PurposeThe purpose of this paper is to identify associations amongst organizational justice, supervisory justice, authoritarian culture, organization-employee relationship quality and employee turnover intention.Design/methodology/approachAn online survey (n=300) was conducted in South Korea.FindingsOrganizational justice and supervisory justice are ...
Kim, Soojin, Tam, Lisa, Kim, Jeong-Nam, Rhee, Yunna   +3 more
openaire   +3 more sources