Results 181 to 190 of about 33,248 (313)

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Relationship Among Workplace Bullying, Job Satisfaction, Burnout, and Turnover Intention: The Mediating Role of Nurses' Resilience. [PDF]

Nurs Res Pract
Souza-Costa AC, Oliveira HC, Guirardello EB.   +2 more
europepmc   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Effects of a psychological capital intervention on emergency nurses' work engagement and turnover intention: A randomized controlled trial. [PDF]

Medicine (Baltimore)
Sun K, Gong X, Yuan G.
europepmc   +1 more source

Quality of work life and turnover intention in primary healthcare organisations : a cross-sectional study of registered nurses in Saudi Arabia

, 2012
Purpose: The purpose of this study was to improve the retention of primary healthcare (PHC) nurses through exploring and assessing their quality of work life (QWL) and turnover intention.\ud Design and methods: A cross-sectional survey design was used in
Almalki, Mohammed Jubran
core  

Spike‐Embedded Nanocatalysts via Metal‐Directed Carbonization for Highly Efficient and Robust Semi‐Hydrogenation

Advanced Science, EarlyView.
A metal‐directed carbonization strategy transforms hierarchical organic microspheres into spiky carbon catalysts with Pd nanoparticles embedded at the tips. This approach resolves the activity‐stability trade‐off, achieving exceptional poison resistance in semi‐hydrogenations, offering a versatile, scalable platform for designing high‐performance ...
Yintao Li, Yang Sun, Minghang Li, Wenxuan Zhang, Zhengtao Li, Yihao Ni, Yao Zhang, Yong Wang, Samuel S. Veroneau, Pengfei Ji   +9 more
wiley   +1 more source

Alarm Fatigue and Turnover Intention Among Haemodialysis Nurses: The Mediating Role of Professional Quality of Life. [PDF]

Nurs Open
Sarmadi S, Sanaie N, Borhani F, Zare-Kaseb A, Nazari AM.   +4 more
europepmc   +1 more source

The Impact of Organizational Justice on Turnover Intention Among Primary Healthcare Workers: The Mediating Role of Work Motivation

Shichao Zhao,1 Zhaofei Ma,1 Hongyu Li,1 Zhanning Wang,1 Ying Wang,2,* Huifen Ma3,* 1School of Public Administration, Shandong Normal University, Jinan, Shandong, People’s Republic of China; 2School of Health Management, Shandong University of ...
Li H, Zhao S, Ma H, Ma Z, Wang Y, Wang Z
core  

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source