Results 191 to 200 of about 1,051,372 (350)

Intrinsic Coordination Architecture Governing Selectivity Divergence Between Extended and Single‐Site Electrocatalysts

open access: yesAdvanced Materials, EarlyView.
Catalyst coordination acts as a loaded dice biasing reaction selectivity. Single‐atom site catalysts lock intermediates in exposed configurations, enabling continued hydrogenation and favoring oxygen‐retaining products. In contrast, extended metal surfaces fully coordinate and shield reactive centers, promoting deoxygenation pathways. This work reveals
Chengyi Zhang, Ziyun Wang
wiley   +1 more source

Engineered Heparinized GQDS/HPEI–Polyamide Membrane for Bilirubin Removal via One Step Anti Coagulation

open access: yesAdvanced Materials Interfaces, EarlyView.
A multifunctional heparinized polyamide membrane embedded with graphene quantum dots (GQDs) and hyperbranched polyethyleneimine (HPEI) is engineered for efficient bilirubin removal via a one‐step anticoagulation–adsorption process. The membrane demonstrates enhanced hemocompatibility, prolonged clotting times, and high bilirubin adsorption capacity ...
Abdur Rehman Mushtaq Ahmad   +6 more
wiley   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

open access: yesAdvanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu   +12 more
wiley   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

open access: yesAdvanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher   +15 more
wiley   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

open access: yesAdvanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang   +14 more
wiley   +1 more source

Anomie as an Antecedent of Nurses' Turnover Intention. [PDF]

open access: yesInt Nurs Rev
Sánchez-Medina AJ   +3 more
europepmc   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

open access: yesAdvanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch   +4 more
wiley   +1 more source

PENGARUH BEBAN KERJA, KOMPENSASI DAN JOB INSECURITY TERHADAP TURNOVER INTENTION YANG DIMEDIASI OLEH KOMITMEN ORGANISASI PADA DOSEN TIDAK TETAP INSTITUT AGAMA ISLAM NEGERI MADURA [PDF]

open access: yes
Penelitian ini bertujuan untuk mengetahui dan menguji peran komitmen organisasi dalam memediasi pengaruh beban kerja, kompensasi dan job insecurity terhadap turnover intention pada dosen tidak tetap IAIN Madura.
Rahman, Abdur   +2 more
core  

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