Results 81 to 90 of about 11,154 (181)

TWAS association signals for SWAM.

, 2022
We used SWAM to derive an tissue-specific model for every GTEx version 6 tissue, and used these models as inputs to metaXcan to infer TWAS results. As mentioned in the Materials and Methods section, the HDL and LDL traits were from Global Lipids Genetics
Hyun Min Kang (9690325), Andrew E. Liu (12024808)   +1 more
core   +1 more source

MAAT: a new nonparametric Bayesian framework for incorporating multiple functional annotations in transcriptome-wide association studies

Genome Biology
Transcriptome-wide association study (TWAS) has emerged as a powerful tool for translating the myriad variations identified by genome-wide association studies (GWAS) into regulated genes in the post-GWAS era.
Han Wang, Xiang Li, Teng Li, Zhe Li, Pak Chung Sham, Yan Dora Zhang   +5 more
doaj   +1 more source

Partial manure substitution in maize‐soybean intercropping reduces ammonia volatilization and increases yield and water‐use efficiency

Agronomy Journal, Volume 118, Issue 6, November/December 2026.
Abstract Intercropping of cereals with legumes is a well‐established strategy for maximizing yield, but its effectiveness in water‐use efficiency (WUE) is not well recognized. This study aimed to investigate the effectiveness of manure and maize‐soybean intercropping on ammonia (NH3) volatilization, yield, and WUE.
Md Raseduzzaman, Wenxu Dong, Md Razzab Ali, Fiston Bizimana, Stephen Okoth Aluoch, Gokul Gaudel, Xiaoxin Li, Chunsheng Hu   +7 more
wiley   +1 more source

Using SWAM to impute expression and conduct TWAS.

, 2022
The first panel shows how SWAM can be used to impute expression levels via prediXcan, while the second panel shows the required inputs to conduct TWAS via metaXcan. (PDF)
Hyun Min Kang (9690325), Andrew E. Liu (12024808)   +1 more
core   +1 more source

Tropical Plantains, Tubers, and Roots: Advancing Food Quality, Safety, and Processing Innovations for Global Nutritional Equity

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Plantains, tubers, and roots (PTRs) represent strategic nutritional and caloric pillars for over 500 million people across tropical regions. This review evaluates traditional bioprocessing against eco‐innovative thermomechanical and non‐thermal technologies (HPP, extrusion, encapsulation) to overcome severe post‐harvest losses and antinutritional risks.
Mundéné‐Timothée Junior Lawrence, Veeranna Hitlamani, Njintang Yanou Nicolas, Aashitosh A. Inamdar   +3 more
wiley   +1 more source

Determining the Genetic Component of Protein Levels with TWAS

, 2022
The central dogma of biology describes how DNA serves as the blueprint for life; genes encoded in DNA get transcribed into RNA molecules, which get translated into proteins. Gene regulation encompasses the variety of mechanisms that control the processes
Wheeler, Heather, Wittich, Henry
core   +1 more source

Potential Functions and Causal Associations of GNLY in Primary Open-Angle Glaucoma: Integration of Blood-Derived Proteome, Transcriptome, and Experimental Verification

Journal of Inflammation Research
Dangdang Wang,1,2,* Yanyu Pu,1,2,* Xi Gao,1,2 Lihong Zeng,1,2 Hong Li1,2 1Department of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Chongqing Key Laboratory for the ...
Wang D, Pu Y, Gao X, Zeng L, Li H
doaj  

Transcriptome-Wide Association Supplements Genome-Wide Association in Zea mays

G3: Genes, Genomes, Genetics, 2019
Modern improvement of complex traits in agricultural species relies on successful associations of heritable molecular variation with observable phenotypes. Historically, this pursuit has primarily been based on easily measurable genetic markers.
Karl A. G. Kremling, Christine H. Diepenbrock, Michael A. Gore, Edward S. Buckler, Nonoy B. Bandillo   +4 more
doaj   +1 more source

Science for All? A Systematic Literature Review on Effective Teaching Approaches in Inclusive and Separate Settings

Science Education, Volume 110, Issue 6, Page 1567-1595, November 2026.
ABSTRACT This systematic literature review examines intervention studies focused on teaching science to a diverse range of learners. It adopts a broad definition of inclusion and makes use of the PRISMA statement. The review aims to provide an overview of evidence‐based teaching approaches in the current literature, identify the science skills targeted,
Silvia Fränkel, Nadine Großmann, Melanie Basten   +2 more
wiley   +1 more source

Natural variation in the promoter of OsPDX1.2 enhances vitamin B6 accumulation and cold tolerance in rice

Journal of Integrative Plant Biology, Volume 68, Issue 11, Page 3914-3928, November 2026.
Allelic variation in the promoter of the pyridoxal phosphate synthase OsPDX1.2 caused variation in the ACE‐box cis‐elements, resulting in differing OsPDX1.2 expression due to differences in binding affinity between the OsbZIP18 transcription factor and the ACE‐box, contributing to variation in vitamin B6 levels and cold tolerance among rice varieties ...
Bi Wang, Qiu Yi Wang, Wen Jie Shi, Rong Hui Li, Xu Dong Zhang, Li Ping Wang, Shi Jia Xia, Kai Xi Chen, Jun Jie Zhou, Yang Yang Sun, Jing He, Alisdair R. Fernie, Ying Chun Han, Jun Zhou Li, Yu Heng Shi, Xian Qing Liu, Yuan Yuan Zhang, Jie Luo, Cheng Jin   +18 more
wiley   +1 more source