Results 81 to 90 of about 56,647 (174)

Twenty‐Year Longitudinal Cohort Study of Cancer Incidence and Mortality Among Workers in Two Primary Aluminum Prebake Smelters

American Journal of Industrial Medicine, Volume 69, Issue 4, Page 269-282, April 2026.
ABSTRACT Background Classified as carcinogenic to humans by the International Agency for Research on Cancer, aluminum production has been transitioning towards lower polycyclic aromatic hydrocarbon‐emitting prebake smelters. This study explored the risk of cancer and mortality over 20 years follow‐up among a cohort of aluminum prebake smelter workers ...
Natasha Kinsman, Christina Dimitriadis, Anthony Del Monaco, Geza Benke, Sophia Xie, Malcolm Sim, StellaMay Gwini, Karen Walker‐Bone   +7 more
wiley   +1 more source

DNA Methylation‐Regulated ZDHHC24 Exacerbates the Risk of Intracranial Aneurysms

Brain and Behavior, Volume 16, Issue 4, April 2026.
Multimodal Mendelian randomization integrating multi‐omics datasets pinpointed four DNA‐methylation loci that act in concert with the palmitoylation gene ZDHHC24 to modulate intracranial aneurysm risk, shedding new light on the molecular etiology of IA susceptibility and highlighting potential therapeutic targets.
Hao Yuan, Can Li, Xin Feng, Jiancheng Lin, Chi Huang, Mengshi Huang, Chuanzhi Duan   +6 more
wiley   +1 more source

Antimicrobial‐Resistance Genetic Markers Among Multidrug‐Resistant Enterobacteriaceae and Acinetobacter spp. From Vegetable Market Chains in Ethiopia

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Schematic overview of the study workflow explaining isolation of lactose‐fermenting Gram‐negative bacteria from farms and supermarkets, antimicrobial susceptibility testing, detection of resistance genes by PCR, and ERIC‐PCR to evaluate genetic diversity and relatedness among isolates.
Hemen Tesfaye, Adey Feleke Desta, Ahu Reis, Mine Egin, Osman Birol Ozgumus, Neslihan Akarsu, Mujib Abdulkadir, Haile Alemayehu, Tadesse Eguale, Ali Osman Kilic   +9 more
wiley   +1 more source

Expression- and splicing-based multi-tissue transcriptome-wide association studies identified multiple genes for breast cancer by estrogen-receptor status

Breast Cancer Research
Background Although several transcriptome-wide association studies (TWASs) have been performed to identify genes associated with overall breast cancer (BC) risk, only a few TWAS have explored the differences in estrogen receptor-positive (ER+) and ...
Julian C. McClellan, James L. Li, Guimin Gao, Dezheng Huo   +3 more
doaj   +1 more source

Surges Control Salt Flux Variability in a Partially‐Mixed Estuary

Journal of Geophysical Research: Oceans, Volume 131, Issue 4, April 2026.
Abstract Salt intrusion is a key parameter characterizing estuarine systems and assessing their response to engineering measures and climate change. Salt intrusion is highly variable as estuaries constantly adapt to changes in discharge, tidal range, and surges. This study is focused on the variations of the salt intrusion in a partially mixed estuary,
M. Becker, C. Consuegra, P. Kolb, F. Kösters, A. Zorndt, C. Winter   +5 more
wiley   +1 more source

FABIO: TWAS fine-mapping to prioritize causal genes for binary traits.

PLoS Genetics
Transcriptome-wide association studies (TWAS) have emerged as a powerful tool for identifying gene-trait associations by integrating gene expression mapping studies with genome-wide association studies (GWAS). While most existing TWAS approaches focus on
Haihan Zhang, Kevin He, Zheng Li, Lam C Tsoi, Xiang Zhou   +4 more
doaj   +1 more source

Skin barrier‐related genes in childhood atopic dermatitis, asthma, and allergy: A systematic review and meta‐analysis

Pediatric Allergy and Immunology, Volume 37, Issue 4, April 2026.
Abstract Atopic dermatitis (AD), asthma, food allergy, and respiratory allergy are common childhood conditions with significant disease burden. Current understanding implicates the skin‐barrier and the dual‐allergen hypotheses in the pathophysiology of these allergic conditions.
I. Husain, K. Patel, C. Holden, L. Jervis, K. Barnard, E. Youssef, J. Felton, S. Bremner, S. J. Brown, S. Mukhopadhyay   +9 more
wiley   +1 more source

Quo Vadis, Posadas? [PDF]

, 1998
This examination looks at Virginia\u27s ban on speech advertising motorcycles and revisits the question raised in the Posadas decision - may a state ban speech about a legal product the state could ban if it so desired.
Van Alstyne, William W.
core   +2 more sources

Uncovering causal gene-tissue pairs and variants through a multivariate TWAS controlling for infinitesimal effects

Nature Communications
Transcriptome-wide association studies (TWAS) are commonly used to prioritize causal genes underlying associations found in genome-wide association studies (GWAS) and have been extended to identify causal genes through multivariate TWAS methods. However,
Yihe Yang, Noah Lorincz-Comi, Xiaofeng Zhu   +2 more
doaj   +1 more source

A genetic study to identify pathogenic mechanisms and drug targets for benign prostatic hyperplasia: a multi-omics Mendelian randomization study

Scientific Reports
Benign prostatic hyperplasia (BPH) as a common geriatric disease in urology, the incidence and prevalence are rapidly increasing with the aging society, prompting an urgent need for effective prevention and treatment of BPH.
Bohan Liu, Xinyi Wang, Zerui Yang, Zhaofa Yin, Cai Tang, Yushi He, Qi Ling, Zhongli Huang, Shijian Feng   +8 more
doaj   +1 more source