Results 91 to 100 of about 6,969,201 (284)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Effect of Tween 20 on the Oxidative Stability of Sodium Linoleate and Sodium Docosahexaenoate

open access: yesBioscience, Biotechnology, and Biochemistry, 1997
Sodium linoleate (LA) and sodium docosahexaenoate (DHA) were oxidized in an aqueous phase with or without Tween 20. The oxidative stability of LA with Tween 20 was slightly less than that of LA without Tween 20. In contrast, when DHA was dispersed in a buffer containing Tween 20, the stability of DHA was markedly increased, suggesting a specific effect
MIYASHITA, Kazuo   +2 more
openaire   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Reversal effect of Tween-20 on multidrug resistance in tumor cells in vitro

open access: yesBiomedicine & Pharmacotherapy, 2012
Multidrug resistance (MDR) is a major barrier for chemotherapy of many cancers. Non-ionic surfactants have great potential to reverse the MDR by preventing onset or delay progression of the carcinogenic process. However, the role of Tween-20 in the development of MDR remains unknown.
Shouhui, Yang   +3 more
openaire   +2 more sources

Einfluss der nichtionischen Tenside Tween® 20, Tween® 80 und Pluronic® F-68 auf die Interaktion von Nanopartikeln mit Caco-2 Einzelzellen [PDF]

open access: yes, 2008
Im Rahmen dieser Diplomarbeit wurde untersucht, welchen Einfluss die nichtionischen Tenside Tween® 20, Tween® 80 und Pluronic® F-68 auf die Interaktion von Nanopartikeln mit Caco-2 DSMZ Einzelzellen ausüben.
Andrlik, Isabella
core  

The effect of Tween-20 additive on the morphology and performance of PVDF membranes

open access: yes, 2015
The effects of additive, Tween-20, on the morphology and ultra-filtration performance of the PVDF membranes formed by isothermal immersion precipitation from the Tween-20/water/TEP/PVDF system were investigated.
Cheng, Liao-Ping   +3 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

In vitro modulation of inflammatory cytokine and IgG levels by extracts of Perna canaliculus

open access: yesBMC Complementary and Alternative Medicine, 2006
Background Inflammation is a predominant characteristic of autoimmune diseases which is characterized by the increased expression of pro-inflammatory cytokines.
Lawson John W, Mani Sachin
doaj   +1 more source

The nuclear tRNA and mRNA export defect caused by Tween-20 is reversible.

open access: yes, 2013
HeLa cells were left in serum-free media (panels A and B, Untreated) or treated with 150 µM Tween-20 for 4 h in serum-free DMEM. The cells were then kept in the presence of Tween-20 (second panel, Tween-20), or washed and placed in fresh serum-free DMEM ...
Jacqueline B. Pierce (312676)   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy