Results 91 to 100 of about 395,966 (258)

Self-emulsifying drug delivery systems as a tool to improve solubility and bioavailability of resveratrol

Drug Design, Development and Therapy, 2016
Gehan F Balata,1 Ebtessam A Essa,1,2 Hanan A Shamardl,3,5 Samira H Zaidan,4 Mohammed AS Abourehab1,6 1Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia; 2Department of Pharmaceutics, Faculty of Pharmacy ...
Balata GF, Essa EA, Shamardl HA, Zaidan SH, Abourehab MAS   +4 more
doaj  

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

PEGylated Tween 80-functionalized chitosan-lipidic nano-vesicular hybrids for heightening nose-to-brain delivery and bioavailability of metoclopramide. [PDF]

Drug Deliv, 2023
Al-Zuhairy SAS, Teaima MH, Shoman NA, Elasaly M, El-Nabarawi MA, El-Sawy HS.   +5 more
europepmc   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Integrated alkaline pretreatment and surfactant-assisted hydrolysis for high-yield Manno-oligosaccharides production from spent coffee grounds

Food Chemistry: X
In this study, a process optimization strategy was established to enhance the efficiency of manno-oligosaccharides (MOS) production from spent coffee grounds (SCG), using a sequential approach of aqueous ammonia pretreatment and surfactant-assisted ...
Donglin Xin, Hong Yin, Zhenni Jiao, Ganqiao Ran   +3 more
doaj   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Enhancement of anaerobic digestion performance of rice straw by Tween 80: Effects, kinetics, and microbial mechanisms

Industrial Crops and Products
Anaerobic digestion (AD) of lignocellulosic biomass such as rice straw (RS) was regarded as an effective way to promote renewable energy development. Optimizing the AD capability of RS has thus drawn considerable research interest.
Xu Wang, Xinzi Wang, Jun Huang, Xiaoyu Zuo   +3 more
doaj   +1 more source

Tween-80 improves single/coaxial electrospinning of three-layered bioartificial blood vessel. [PDF]

J Mater Sci Mater Med, 2022
Wu C, Wang H, Cao J.
europepmc   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Effect of Tween 20 and 80 Addition During the Chopping Process on Gel Quality of Silver Carp Surimi

Foods
The impact of nonionic surfactant (Tween 20 and Tween 80) addition during the chopping process on the surimi gel quality was investigated. Results showed that the addition of Tween 20 or Tween 80 significantly decreased myofibrillar protein solubility in
Yu Zhang, Yulong Bao, Yuemei Zhang, Yi-Ming Zhao   +3 more
doaj   +1 more source