Results 41 to 50 of about 35,700 (291)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Deformation twinning in nanocrystalline materials

open access: yes, 2012
Nanocrystalline (nc) materials can be defined as solids with grain sizes in the range of 1–100 nm. Contrary to coarse-grained metals, which become more difficult to twin with decreasing grain size, nanocrystalline face-centered-cubic (fcc ...
Zhu YT, Liao XZ, 武晓雷
core   +2 more sources

Hierarchical {332}<113> twinning in a metastable β Ti-alloy showing tolerance to strain localization

open access: yesMaterials Research Letters, 2020
A hierarchical {332} twinning system is studied in a metastable beta Ti-12Mo-10Zr (wt%) alloy, which shows strong twinning-induced plasticity (TWIP) effect due to a three-level twinning mechanism.
Jinyong Zhang   +10 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Transmutation of zonal twinning dislocations during non-cozone {101¯1} twin-twin interaction in magnesium

open access: yesJournal of Magnesium and Alloys
Theoretically, a twinning dislocation must stay on the twinning plane which is the first invariant plane of a twinning mode, because the glide of twinning dislocation linearly transforms the parent lattice to the twin lattice.
Peng Chen, Bin Li
doaj   +1 more source

Mechanism of {332}<113> Twinning Formation in Cold-Rolled Ti-Nb-Ta-Zr-O Alloy

open access: yesMetals, 2018
In this study, the mechanism of {332}<113> twinning formation in cold-rolled Ti-35Nb-2Ta-3Zr-O (wt %) alloy was investigated based on the Taylor-Bishop-Hill theory.
Jinhui Sun, Leng Chen
doaj   +1 more source

Deformation Twinning In Bulk Nanocrystalline Metals: Experimental Observations

open access: yes, 2008
Deformation twins have been observed in nanocrystalline (nc) fcc metals with medium-to-high stacking fault energies such as aluminum, copper, and nickel.
Zhu, YT (reprint author), N Carolina State Univ, Dept Mat Sci & Engn, Box 7907, Raleigh, NC 27695 USA.   +3 more
core   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

Twinning between national immunization technical advisory groups: an innovative approach to strengthening evidence-informed immunization policy in the Americas

open access: yesVaccine: X
Background: National Immunization Technical Advisory Groups (NITAGs) play a key role in evidence-informed immunization policy. To strengthen their capacity, a regional twinning initiative was introduced in the Americas to promote peer-to-peer ...
N. Jennifer Sanwogou   +9 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy