Results 71 to 80 of about 29,018 (198)
TWIST1 Plays a Pleiotropic Role in Determining the Anaplastic Thyroid Cancer Phenotype [PDF]
, 2011 10 páginas, 5 figuras, 1 tabla.-- et al.[Context]:Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human tumors; it is characterized by chemoresistance, local invasion, and distant metastases. ATC is invariably fatal.
García-Rostan, Ginesa, Salerno, Paolo
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De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development [PDF]
, 2017 Bosma arhinia microphthalmia syndrome (BAMS) is an extremely rare and striking condition characterized by complete absence of the nose with or without ocular defects.
A Javed +97 more
core +3 more sources
Roles of Twist1 in lipid and glucose metabolism
Cell Communication and Signaling, 2023 AbstractThe abnormal lipid and glucose metabolisms are linked to the metabolic disorders, tumorigenesis, and fibrotic diseases, which attracts the increasing attention to find out the key molecules involved in the lipid and glucose metabolism as the possible therapeutic targets on these diseases. A transcriptional factor Twist1 has been associated with
Liuyifei Huang +6 more
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Reactivation of TWIST1 contributes to Ewing sarcoma metastasis [PDF]
Pediatric Blood & Cancer, 2017 AbstractBackgroundEwing sarcoma is a cancer of bone and soft tissue. Despite aggressive treatment, survival remains poor, particularly in patients with metastatic disease. Failure to treat Ewing sarcoma is due to the lack of understanding of the molecular pathways that regulate metastasis.
Sun Choo +4 more
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TWIST1 hypermethylation is observed in pancreatic cancer
Biomedical Reports, 2012 Despite the growing evidence demonstrating that TWIST1 is a noteworthy tumor biomarker, little is known about the clinical significance of TWIST1 methylation in human primary pancreatic cancer. In the present study, the association of TWIST1 methylation with clinicopathological characteristics was examined in human primary pancreatic cancer.
Manabu, Sen-Yo +3 more
openaire +3 more sources
A noninvasive multi-analyte diagnostic assay: Combining protein and DNA markers to stratify bladder cancer patients [PDF]
, 2012 Purpose: The authors recently reported the development of a noninvasive diagnostic assay using urinary matrix metalloproteinases (MMPs) as monitors of disease-free status and bladder cancer in high-risk populations.
Feldman, A.S. (Adam S) +5 more
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Multi-Cancer Computational Analysis Reveals Metastasis-Associated Variant of Desmoplastic Reaction Involving INHBA and THBS2 [PDF]
, 2010 Despite extensive research, the details of the metastasis-associated biological mechanisms are largely unknown. Here, we analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression ...
Dimitris Anastassiou +3 more
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Enhanced expression of the stemness-related factors OCT4, SOX15 and TWIST1 in ectopic endometrium of endometriosis patients [PDF]
, 2016 Background Current evidence suggests that endometrial-derived stem cells, spilled in the peritoneal cavity via retrograde menstruation, are key players in the establishment of endometriotic lesions. The aim of this study was to determine the presence and
Berthold Streubel +10 more
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PLoS ONE, 2019 Steroid receptor coactivator 1 (Src-1) and Twist1 are aberrantly upregulated in a variety of tumors and play an important role in tumor progression. However, the exact role of Src-1 and Twist1 in nasopharyngeal carcinoma (NPC) is uncertain. In this study,
Jingchun Zhou +5 more
doaj +1 more source
Cellular & Molecular Biology Letters, 2017 Background The transcription factor TWIST1 plays an important role in the epithelial–mesenchymal transition (EMT) process and in the migration, invasion and metastasis of cancer cells. OCT4, which is a homeobox transcription factor, has an important role
Mohammad Hossein Izadpanah +3 more
doaj +1 more source