Results 201 to 210 of about 1,641,408 (271)

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

Advanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo, Katie Shi, Lina Kafadarian, Alexandra Bermudez, Johnny Diaz, Liam Edwards, Yunqi Hong, Ziyi Chen, Hyeonji Hwang, Weihong Yan, Alan Levinson, Robert Damoiseaux, Cho‐Jui Hsieh, Tanya Stoyanova, Andrew S. Goldstein, Neil Y.C. Lin   +15 more
wiley   +1 more source

Correlated insulating states in slow Dirac fermions on a honeycomb moiré superlattice. [PDF]

Nat Commun
Yang D, Liang J, Hu H, Kaushal N, Hsu CE, Watanabe K, Taniguchi T, Dadap JI, Li Z, Franz M, Ye Z.   +10 more
europepmc   +1 more source

Hardware‐Native Gaussian Sampling With Probabilistic Ising Machines for Modern Communication Paradigms

Advanced Science, EarlyView.
Probabilistic Ising machines are introduced as hardware‐native Gaussian samplers for edge communication workloads. Tunable variance and sampling density enable accurate distributions for Falcon‐class post‐quantum signatures and diffusion‐based semantic communication.
Davi Rodrigues, Andrea Grimaldi, Deborah Volpe, Youwei Bao, Shuhan Yang, Eleonora Grassucci, Giulio Siracusano, Massimo Chiappini, Mario Carpentieri, Hyunsoo Yang, Giovanni Finocchio   +10 more
wiley   +1 more source

Engineering moiré potentials in twisted bilayer MoS₂ for selective single-molecule sensing. [PDF]

Nat Commun
Zhao M, He H, Wang Z, Bai Y, Chang L, Sun L, Wang C, Gao J, Li W, Liu X, Zhang T, Zhang J, Zhang N, Gan L, Liu B, Li J, Terrones M, Lei Y.   +17 more
europepmc   +1 more source

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

Advanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi, Tiziana Cremona, Reto Czekalla, Emily Campbell, Marlene Schwarzfischer, Doris Pöhlmann, Vanessa Dobernig, Gerhard Rogler, Michael Scharl, Alessandra Bergadano, Raffaele Mezzenga, Martin Kuentz, Paola Luciani, Simone Aleandri   +13 more
wiley   +1 more source

Evaluating AlphaFold Tools and Related Scoring Functions for Protein-peptide Complex Prediction. [PDF]

Genomics Proteomics Bioinformatics
Manshour N, Ren JZ, Esmaili F, Bergstrom E, Xu 许东 D.   +4 more
europepmc   +1 more source

Skyrmion Bubbles by Design in a Centrosymmetric Kagome Magnet

Advanced Science, EarlyView.
Chemical tuning of magnetocrystalline anisotropy in the centrosymmetric kagome magnet TmMn6Sn6 is shown to drive a spin reorientation transition via an intermediate magnetic fan state and to stabilize an emergent skyrmion bubble lattice. Four‐dimensional cryogenic Lorentz scanning transmission electron microscopy confirms the nanoscale texture ...
Mohamed El Gazzah, Fehmi Sami Yasin, Sk Jamaluddin, Hari Bhandari, Resham Babu Regmi, Xiuzhen Yu, Nirmal J. Ghimire   +6 more
wiley   +1 more source

Strong interlayer coupling and chiral flat-band cascades in twisted bilayer gratings. [PDF]

Sci Adv
Choi D, Lee SJ, Cho SW, Bark CB, Pak S, Shin DJ, Park MJ, Gong SH.   +7 more
europepmc   +1 more source

Unlocking the Full Potential of Jumping Condensation on Microstructured Surfaces

Advanced Science, EarlyView.
Microcone arrays exhibit a spacing‐dependent transition between jumping and non‐jumping condensation. Dense microstructures favor full Cassie droplets, which depart cleanly, while wider spacing favors partial Cassie droplets that retain a localized wet region initiating new nucleation. These findings establish a link between microdroplet morphology and
Mariia S. Kiseleva, Tytti Kärki, Mika Latikka, Parham Koochak, Sakari Lepikko, Maja Vuckovac, Tomi Koskinen, Ramesh Raju, Ville P. Jokinen, Jiazheng Liu, Nenad Miljkovic, Jaakko V. I. Timonen, Ilkka Tittonen, Robin H. A. Ras   +13 more
wiley   +1 more source

Reconfiguring handed shape-morphing and actuation in hydrogels via light-encoded rapid expansion. [PDF]

Nat Commun
Chu Z, Zhou Z, Jin K, He L, Li C.
europepmc   +1 more source