Results 81 to 90 of about 788,319 (263)

Facet-selective growth of halide perovskite/2D semiconductor van der Waals heterostructures for improved optical gain and lasing

Nature Communications
The tunable properties of halide perovskite/two dimensional (2D) semiconductor mixed-dimensional van der Waals heterostructures offer high flexibility for innovating optoelectronic and photonic devices.
Liqiang Zhang, Yiliu Wang, Anshi Chu, Zhengwei Zhang, Miaomiao Liu, Xiaohua Shen, Bailing Li, Xu Li, Chen Yi, Rong Song, Yingying Liu, Xiujuan Zhuang, Xidong Duan   +12 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Anomalous twin boundaries in two dimensional materials

Nature Communications, 2018
All materials subjected to mechanical deformation form low energy interfaces known as twin boundaries. Here, the authors investigate a variety of structural features that form upon bending atomically thin 2D-crystals, and predict distinct classes of post
A. P. Rooney, Z. Li, W. Zhao, A. Gholinia, A. Kozikov, G. Auton, F. Ding, R. V. Gorbachev, R. J. Young, S. J. Haigh   +9 more
doaj   +1 more source

Imaging Two Dimensional Materials and their Heterostructures

Journal of Physics: Conference Series, 2017
Stacking different two-dimensional (2D) atomic layers is a feasible approach to create unique multilayered van der Waals heterostructures with desired properties. 2D materials, graphene, hexagonal boron nitride (h-BN), molybdenum disulphate (MoS2) and graphene based van der Waals heterostructures, such as h-BN/graphene and MoS2/graphene have been ...
Zan, R, Ramasse, QM, Jalil, R, Tu, J-S, Bangert, U, Novoselov, KS   +5 more
openaire   +3 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

MXene-MoS2 engineered heterostructured vertical memristors array: high-performance non-volatile memory with scalable integration

npj 2D Materials and Applications
The emergence of artificial intelligence and neuromorphic computing has revealed the importance of two-dimensional (2D) layered materials in the field of non-volatile memory technologies.
Kubra Sattar, Ivan S. Babichuk, Saleem Ayaz Khan, Jian Yang, Syed Rizwan   +4 more
doaj   +1 more source

Current Rectification in a Structure: ReSe2/Au Contacts on Both Sides of ReSe2

Nanoscale Research Letters, 2019
Schottky effect of two-dimensional materials is important for nanoscale electrics. A ReSe2 flake is transferred to be suspended between an Au sink and an Au nanofilm.
Tingting Miao, Dongwei Yu, Lei Xing, Dawei Li, Liying Jiao, Weigang Ma, Xing Zhang   +6 more
doaj   +1 more source