Results 71 to 80 of about 31,594,956 (291)

Computational investigation of liquid-solid slurry flow through an expansion in a rectangular duct

Journal of Hydrology and Hydromechanics, 2014
The flow of a mixture of liquid and solid particles at medium and high volume fraction through an expansion in a rectangular duct is considered. In order to improve the modelling of the phenomenon with respect to a previous investigation (Messa and ...
Vittorio Messa Gianandrea, Malavasi Stefano   +1 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The Imploding Cylindrical Richtmyer-Meshkov Instability with Ideal Two-Fluid Plasma Model

, 2019
The shock-interface interaction in converging flow in the presence of magnetic field is numerically studied with two-fluid plasma model. Two-fluid effect on the density field is investigated by varying Debye length: the electron and ion dynamics ...
W. Cheng, Y. Li, Bond, Daryl, V. Wheatley, Samtaney, Ravi, Cheng, W., R. Samtaney, Li, Y., Wheatley, V., Daryl Bond   +9 more
core   +1 more source

Dissipative Two-Fluid Models

, 2006
From Hamilton's principle of stationary action, we derive governing equations of two-fluid mixtures and extend the model to the dissipative case without chemical reactions. For both conservative and dissipative cases, an algebraic identity connecting equations of momentum, mass, energy and entropy is obtained by extending the Gibbs identity in dynamics.
Gouin, Henri, Gavrilyuk, Sergey
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Numerical Simulation of the Isoparaffins Dehydrogenation Process in Fluidized Bed Reactor: From Laboratory to Industry

ChemEngineering
A numerical model was developed to simulate a fluidized bed reactor for isobutane dehydrogenation. First, we constructed a hydrodynamic model of catalyst particle fluidization and a kinetic model for three chemical reactions in a simple lab-scale reactor
Sergei A. Solovev, Olga V. Soloveva
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Two-Fluid Models of Turbulence [PDF]

, 1985
It has become customary among engineers and others concerned with practical flow and heat-transfer predictions to use “turbulence models”, le sets of equations which purport. when coupled with the equations of mean motion, to describe such statistically significant properties as the “effective viscosity”. “length scale” and “energy”.
openaire   +1 more source