Results 81 to 90 of about 31,594,956 (291)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Physics of Neutron Star Crusts
The physics of neutron star crusts is vast, involving many different research fields, from nuclear and condensed matter physics to general relativity.
Chamel Nicolas, Haensel Pawel
doaj
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Two-fluid model to simulate metal powder bed fusion additive manufacturing
This paper reports our simulations of the metal powder fusion additive manufacturing process based on a two-fluid model. In simulations of metal behavior in which heat is applied by high-density energy sources (e.g., laser or electron beam), the aspects ...
Noriko WATARI +8 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Research Progress on Relaxed Two-pressure Two-fluid Model and Algorithm
An accurate two-phase flow model is an important basis for nuclear reactor safety analysis. The classical two-fluid six-equation model used in many current thermal-hydraulic programs has an ill-posed problem, if a small disturbance is introduced, the ...
SHAN Jianqiang;WU Zhao;CHAO Fei
doaj
The hole cleaning device is a powerful application which can effectively slow down the deposition of cuttings during drilling. However, in this complicated swirl flow created by the device, the decay of the swirl flow and the particle behavior are not ...
Jingyu Qu +4 more
doaj +1 more source
The quasi-geostrophic ellipsoidal vortex model [PDF]
We present a simple approximate model for studying general aspects of vortex interactions in a rotating stably-stratified fluid. The model idealizes vortices by ellipsoidal volumes of uniform potential vorticity, a materially conserved quantity in an ...
McKiver, William J +4 more
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Flow past one and two adjacent square cylinders based on a two-fluid turbulence model
This paper presents an improved version of the Spalding two-fluid turbulence model developed by Malikov. The model is applied to numerically simulate turbulent flows past one and two square cylinders at a Reynolds number of Re = 47,000.
Madaliev Murodil +3 more
doaj +1 more source

