Results 81 to 90 of about 31,594,956 (291)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Physics of Neutron Star Crusts

open access: yesLiving Reviews in Relativity, 2008
The physics of neutron star crusts is vast, involving many different research fields, from nuclear and condensed matter physics to general relativity.
Chamel Nicolas, Haensel Pawel
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Two-fluid model to simulate metal powder bed fusion additive manufacturing

open access: yesJournal of Fluid Science and Technology, 2018
This paper reports our simulations of the metal powder fusion additive manufacturing process based on a two-fluid model. In simulations of metal behavior in which heat is applied by high-density energy sources (e.g., laser or electron beam), the aspects ...
Noriko WATARI   +8 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Research Progress on Relaxed Two-pressure Two-fluid Model and Algorithm

open access: yesYuanzineng kexue jishu, 2023
An accurate two-phase flow model is an important basis for nuclear reactor safety analysis. The classical two-fluid six-equation model used in many current thermal-hydraulic programs has an ill-posed problem, if a small disturbance is introduced, the ...
SHAN Jianqiang;WU Zhao;CHAO Fei
doaj  

Decaying Swirl Flow and Particle Behavior through the Hole Cleaning Device for Horizontal Drilling of Fossil Fuel

open access: yesEnergies, 2019
The hole cleaning device is a powerful application which can effectively slow down the deposition of cuttings during drilling. However, in this complicated swirl flow created by the device, the decay of the swirl flow and the particle behavior are not ...
Jingyu Qu   +4 more
doaj   +1 more source

The quasi-geostrophic ellipsoidal vortex model [PDF]

open access: yes, 2004
We present a simple approximate model for studying general aspects of vortex interactions in a rotating stably-stratified fluid. The model idealizes vortices by ellipsoidal volumes of uniform potential vorticity, a materially conserved quantity in an ...
McKiver, William J   +4 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Flow past one and two adjacent square cylinders based on a two-fluid turbulence model

open access: yesJournal of Hydrology and Hydromechanics
This paper presents an improved version of the Spalding two-fluid turbulence model developed by Malikov. The model is applied to numerically simulate turbulent flows past one and two square cylinders at a Reynolds number of Re = 47,000.
Madaliev Murodil   +3 more
doaj   +1 more source

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