Results 241 to 250 of about 20,254,963 (292)

Multibeam continuous axial scanning two-photon microscopy for in vivo volumetric imaging in mouse brain. [PDF]

Biomed Opt Express
Ataka M, Otomo K, Enoki R, Ishii H, Tsutsumi M, Kozawa Y, Sato S, Nemoto T.   +7 more
europepmc   +1 more source

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

Advanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu, Priyanka G. Bhosale, Vishal Kumar, Jeyrroy Gabriel, Shiyue Liu, Ciro Chiappini, Richard J. Cook, Mads S. Bergholt   +7 more
wiley   +1 more source

Multidimensional quantitative characterization of basal cell carcinoma by spectral- and time-resolved two-photon microscopy. [PDF]

Nanophotonics
Guo F, Lin F, Shen B, Wang S, Li Y, Guo J, Chen Y, Liu Y, Lu Y, Hu R, He J, Liao C, Wang Y, Qu J, Liu L.   +14 more
europepmc   +1 more source

Combined flat-field and frequency filter approach to correcting artifacts of multichannel two-photon microscopy. [PDF]

J Biomed Opt
Knapp T, Lima N, Daigle N, Duan S, Merchant JL, Sawyer TW.   +5 more
europepmc   +1 more source

Investigating the impact of 2-OHOA-embedded liposomes on biophysical properties of cancer cell membranes via Laurdan two-photon microscopy imaging. [PDF]

Sci Rep
Rui X, Okamoto Y, Fukushima S, Morishita Watanabe N, Umakoshi H.   +4 more
europepmc   +1 more source

Deep Tissue Two-Photon Microscopy

Nature Methods, 2005
With few exceptions biological tissues strongly scatter light, making high-resolution deep imaging impossible for traditional-including confocal-fluorescence microscopy. Nonlinear optical microscopy, in particular two photon-excited fluorescence microscopy, has overcome this limitation, providing large depth penetration mainly because even multiply ...
Winfried Denk, Fritjof Helmchen
exaly   +7 more sources

Two-Photon Microscopy of Cells and Tissue [PDF]

Circulation Research, 2004
Two-photon excitation fluorescence imaging provides thin optical sections from deep within thick, scattering specimens by way of restricting fluorophore excitation (and thus emission) to the focal plane of the microscope. Spatial confinement of two-photon excitation gives rise to several advantages over single-photon confocal microscopy.

exaly   +3 more sources

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Two-Photon Phosphorescence Lifetime Microscopy

2021
Two-photon Phosphorescence Lifetime Microscopy (2PLM) is an emerging nonlinear optical technique that has great potential to improve our understanding of the basic biology underlying human health and disease. Although analogous to 2-photon Fluorescence Lifetime Imaging Microscopy (2P-FLIM), the contrast in 2PLM is fundamentally different from various ...
Nastaran, Abbasizadeh, Joel A, Spencer
openaire   +2 more sources

Two-photon Microscopy Of Tissues

2003
Tissue physiology and pathology can be better understood using two-photon microscopy that allows tissue structure and biochemistry to be assayed on the subcellular level. Histological analysis provides high-resolution tissue characterization and is the only imaging method that can be applied to tissues of arbitrary thicknesses.
Peter T. C. So, Ki H. Kim, Lily Hsu, Peter Kaplan, Tom Hacewicz, Chen Y. Dong, Urs Greuter, Nick Schlumpf, Christof Buehler   +8 more
openaire   +1 more source