Results 71 to 80 of about 660,441 (286)

Children’s Play Profiles: Contributions From Child’s Temperament and Father’s Parenting Styles in a Portuguese Sample

open access: yesFrontiers in Psychology, 2020
Using a sample of Portuguese preschool-age children, we aimed to identify different play profiles based on teachers’ descriptions of social and non-social behaviors, as well as characterize them in terms of children’s characteristics (sex and temperament)
Carolina Santos   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Directionality of physical and psychological dating violence among adolescents in Recife, Brazil

open access: yesRevista Brasileira de Epidemiologia, 2014
OBJECTIVE: The aim was to investigate the physical and psychological dating violence among adolescents with respect to the profiles of directionality - only man perpetrates, only woman perpetrates, and bidirectional, ie, both perpetrate violence ...
Alice Kelly Barreira   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Does integration of ESG disclosure and green financing improve firm performance: Practical applications of stakeholders theory

open access: yesHeliyon
Drawing on the lens of stakeholder theory, this paper explores the association between ESG disclosure, green finance, and the performance of Chinese firms, while considering the moderating role of competitive edge in terms of financing costs.
Ashfaq Habib   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Model-Assisted Estimation of Population Mean in Two-Stage Cluster Sampling

open access: yesPakistan Journal of Statistics and Operation Research, 2017
Estimation of finite population parameters has been an area of concern to statisticians for decades. This paper presents an estimation of the population mean under a model-assisted approach. Dorfman (1992), Breidt and Opsomer (2000) and Ouma et al (2010) carried out the estimation of finite population total on the assumption that the sample size is ...
Bii, Nelson Kiprono   +1 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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