Results 61 to 70 of about 1,618,729 (319)

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Individual participant data meta-analysis for a binary outcome: one-stage or two-stage? [PDF]

PLoS ONE, 2013
A fundamental aspect of epidemiological studies concerns the estimation of factor-outcome associations to identify risk factors, prognostic factors and potential causal factors.
Thomas P A Debray, Karel G M Moons, Ghada Mohammed Abdallah Abo-Zaid, Hendrik Koffijberg, Richard David Riley   +4 more
doaj   +1 more source

Improving on two-stage estimators for scale families

Metrika, 1989
Consider the problem of finding an estimator for a scale parameter such that its risk function is bounded by a preassigned constant. As a solution of the problem, two-stage estimators based on only the second sample have been proposed. The paper shows that these estimators can be improved by combining the first and the second sample.
openaire   +2 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

A sampling plan for residentially generated solid waste quantification at urban zones of middle sized cities

Revista Facultad de Ingeniería Universidad de Antioquia, 2013
We propose a sampling plan intended for medium size cities. The proposed plan begins with a two-stage pilot plan, which helped us to obtain a better estimation of the final sample size when a ratio estimator is used.
Rafael A Klinger, Javier Olaya, Luis Marmolejo, Carlos Madera   +3 more
doaj   +1 more source

A jackknife variance estimator for self-weighted two-stage samples

, 2013
Self-weighted two-stage sampling designs are popular in practice as they simplify field-work. It is common in practice to compute variance estimates only from the first sampling stage, neglecting the second stage.
Berger, Y.G., Escobar, E.L.
core   +1 more source

Estimation under two stage random permutation models [PDF]

Metrika, 1985
In a simple two-stage random permutation model the units which have fixed but unknown values \(x_{ij}\) of the study variate x, are labelled randomly in two stages, first the psu's are labelled at random and then the ssu's within each of the psu's are labelled at random independently.
V. R. Padmawar, V. R. Padmawar, Parimal Mukhopadhyay, Parimal Mukhopadhyay   +3 more
openaire   +2 more sources

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

A Streaming Data Clustering Method Based on Dual Strategies Improved DENCLUE

IEEE Access
Streaming data arrives continually and is characterized by fast, massive, dynamic evolution and instability. Different from traditional static data clustering, streaming data clustering algorithms need to consider concept drift, outlier handling ...
Ting Cai, Jiazhi Lv, Zhiwei Ye, Xiang Li, Wen Zhou, Orest Kochan   +5 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source