Results 101 to 110 of about 2,183,210 (336)
Peroxisome Proliferator-activated receptor alpha gene variation influences age of onset and progression of type 2 diabetes [PDF]
, 2005 Dysregulation of fatty acid metabolism is important in the pathogenesis of type 2 diabetes. Peroxisome proliferator-activated receptor (PPAR) is a master regulator of fatty acid catabolism, and PPAR activators delay the onset of type 2 diabetes.
Acharya, J. +7 more
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The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
Type 1 diabetes mellitus-common cases
Indian Journal of Endocrinology and Metabolism, 2015 Tight glycemic control in type 1 diabetes mellitus patients is associated with the risk of hypoglycemia. Diabetic patients are forced to change their lifestyle to adjust to the disease condition and survive it. The best way to manage diabetes would be to
Surender Kumar
doaj +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
The Foundation Years, 2002 Abstract Failure of the thyroid gland requires thyroid hormone replacement therapy, which is relatively easily adjusted to replicate the normal physiological state by monitoring plasma levels of thyroxine and/or thyroid-stimulating hormone. In contrast, failure of pancreatic b-cells requires insulin therapy, and optimal replacement requires monitoring,
openaire +3 more sources
Pramlintide but Not Liraglutide Suppresses Meal-Stimulated Glucagon Responses in Type 1 Diabetes [PDF]
, 2017 Postprandial hyperglycemia remains a challenge in type 1 diabetes (T1D) due, in part, to dysregulated increases in plasma glucagon levels after ...
Carria, Lori +9 more
core +1 more source
Earthing effects on mitochondrial function: ATP production and ROS generation
FEBS Open Bio, EarlyView.In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley +1 more source
The role of T cell miRNAs for regulatory T cell induction in islet autoimmunity
Molecular Metabolism, 2019 Background: microRNAs (miRNAs) have emerged as critical contributors to immune regulation and homeostasis, and their dysregulation is involved in the aberrant differentiation and function of T cell subsets.
Martin G. Scherm +3 more
doaj
Type 1 diabetes pathogenesis - Prevention???
Indian Journal of Endocrinology and Metabolism, 2015 Pathogenesis of type 1 diabetes is multi-faceted, including, autoimmunity, genetics and environment. Autoimmunity directed against pancreatic islet cells results in slowly progressive selective beta-cell destruction ("Primary autoimmune insulitis ...
C S Muralidhara Krishna, S Srikanta
doaj +1 more source
Reconsidering your perceptions: exploring the lifeworld of a young person with type 1 diabetes [PDF]
, 2013 Introduction Views of young people with type 1 diabetes are vital in developing quality services, yet research on their lifestyle and use of web and mobile technology to support their condition is sparse. We aimed to develop a deeper understanding of the
Hill, J., Masding, M.G., Pulman, Andy
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