Results 81 to 90 of about 1,499,825 (316)

Sample size requirements for studies of treatment effects on beta-cell function in newly diagnosed type 1 diabetes. [PDF]

PLoS ONE, 2011
Preservation of β-cell function as measured by stimulated C-peptide has recently been accepted as a therapeutic target for subjects with newly diagnosed type 1 diabetes.
John M Lachin, Paula L McGee, Carla J Greenbaum, Jerry Palmer, Mark D Pescovitz, Peter Gottlieb, Jay Skyler, Type 1 Diabetes Trial Network   +7 more
doaj   +1 more source

Role of cytokines in the pathogenesis of type 1 diabetes [PDF]

, 1996
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.T lymphocytes and macrophages appear to play an important role in mediating ß-cell damage and causing Type 1 diabetes.
Hussain, Munther Jaffar
core  

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Phase angle and body composition in long-term type 1 diabetes in adults: a comparative study in a Brazilian public reference outpatient clinic

Diabetology & Metabolic Syndrome
Introduction Type 1 Diabetes Mellitus (DM1) affects a small percentage of the population. Nevertheless, its prevalence is currently growing with alarming data on uncontrolled cases.
Natália Fenner-Pena, Virgínia Capistrano Fajardo, Lívia Froes, Paulo Augusto Miranda Carvalho, Fábio Vasconcellos Comim, Viviane Sahade, Márcio Weissheimer Lauria, Henrique Oswaldo da Gama Torres   +7 more
doaj   +1 more source

Network-Level Structural Abnormalities of Cerebral Cortex in Type 1 Diabetes Mellitus [PDF]

, 2013
Type 1 diabetes mellitus (T1DM) usually begins in childhood and adolescence and causes lifelong damage to several major organs including the brain. Despite increasing evidence of T1DM-induced structural deficits in cortical regions implicated in higher ...
Hyeonseok S Jeong, Gail Musen, Hyeonseok S. Jeong (449823), In Kyoon Lyoo (399200), Weinger, K, Weinger Katie, Sujin Bae (279960), Jiyoung J. Jung (399196), Bolo, Nicolas, Bae, Sujin, Donald C. Simonson (297772), Bae, S, Lyoo In Kyoon, Lyoo, In Kyoon, Gail Musen (449820), Nicolas Bolo, Yoon, Sujung, Yera Choi (399197), Lyoo, IK, Jacobson, Alan M., Jieun E. Kim (449821), Ryan, CM, Simonson, Donald, Sujin Bae, Sujung Yoon (399194), Katie Weinger, Jeong Hyeonseok S., Simonson, Donald C., Christopher M. Ryan (410965), Hwang, J, Choi, Yera, Zuo, Xi-Nian, Kim Jieun E., Sujung Yoon, Bae Sujin, Bolo, N, Alan M Jacobson, Alan M. Jacobson (399199), Jeong, Hyeonseok S., Renshaw, PF, Jeong, HS, Sun Hea Lee (449824), Musen, G, Hwang Jaeuk, Simonson Donald C., Lee Sun Hea, Jacobson, AM, Lee, Sun Hea, Yera Choi, Perry F Renshaw, Ryan, Christopher M., Christopher M Ryan, Jung, JJ, Musen Gail, Jung Jiyoung J., In Kyoon Lyoo, Perry F. Renshaw (286262), Choi, Y, Renshaw, Perry F., Jiyoung J Jung, Hwang, Jaeuk, Kim, Jieun E., Yoon Sujung, Lee, SH, Jung, Jiyoung J., Weinger, Katie, Yoon, S, Kim, JE, Katie Weinger (449825), Choi Yera, Renshaw Perry F., Ryan Christopher M., Jacobson Alan M., Musen, Gail, Jaeuk Hwang, Donald C Simonson, Sun Hea Lee, Bolo Nicolas, Jieun E Kim, Jaeuk Hwang (449819), Nicolas Bolo (449822), Simonson, DC   +81 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Prevalence of type 1 diabetes among children aged 0–14 in Australia 2013 [PDF]

, 2015
Prevalence of type 1 diabetes among children aged 0–14 in Australia 2013 presents the first national picture of children aged 0–14 living with type 1 diabetes in Australia.
Sarah Bullock, Karen Byng
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Autoantibodies in type 1 diabetes

Autoimmunity, 2008
Diabetes mellitus is a disorder characterized by hyperglycemia in both the fasting and post-prandial states. The two most common forms of diabetes mellitus, type 1 and type 2 (previously called juvenile-onset and adult-onset, respectively), comprise the vast majority of cases.
Craig E, Taplin, Jennifer M, Barker
openaire   +2 more sources