Results 71 to 80 of about 1,499,825 (316)

Adipose-derived mesenchymal stromal/stem cells in type 1 diabetes treatment

Communications Biology
Adipose tissue-derived mesenchymal stromal/stem cells (ADMSCs) represent a novel therapeutic intervention for Type 1 Diabetes (T1D). The attractiveness of ADMSCs is characterized by their immunomodulatory activities, regenerative properties, and relative
Vanshika Sood, Hannah Ricioli, George Chigozie Njoku, Rosita Primavera, Susana Dietrich, Avnesh S. Thakor, Flemming Pociot, Reza Yarani   +7 more
doaj   +1 more source

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes:rationale and design of the epidemiological studies within the IMI DIRECT Consortium [PDF]

, 2014
Aims/hypothesisThe DIRECT (Diabetes Research on Patient Stratification) Study is part of a European Union Framework 7 Innovative Medicines Initiative project, a joint undertaking between four industry and 21 academic partners throughout Europe.
Rauh, S., Jablonka, B, Bernd Jablonka, Teare, Harriet J A, Frost, G.S., Ridderstråle, Martin, Herrgard, S., Hattersley, A, McDonald, T. J., Sanna Herrgård, Franks, Paul W., Bell, J., Cederberg, Henna, Hansen, TH, Andrea Mari, Pedersen, Oluf, Siloaho, Maritta, Mark Walker, Pearson, Ewan; id_orcid, Pearson, Ewan, Heymans, Martijn W., Perry, MH, Hansen, T.H., Rauh, S, Veikko Koivisto, Ridderstråle, Martin,, McDonald, T.J., Brunak, Søren, Cederberg, H., Barnett, A, Heymans, MartijnW., Frost, G, Vestergaard, H., Hattersley, Andrew T., Franks, P.W., Perry, Mandy, Laakso, M., Consortium, Direct, Paul W. Franks, Barnett, A., Heggie, A., Hansen, T., Thorand, Barbara, Heymans, MW, Siloaho, M., null null, Maritta Siloaho, Koivula, RW, Henrik Vestergaard, Hansen, Tue H., Alison Heggie, Lund University., Teare, Harriet J. A., Hansen, Tue H, Ewan Pearson, Ruetten, H, Hansen, T, Ramneek Gupta, Dekker, Jacqueline M, Rutters, Femke, Walker, M, Koopman, Anitra D, Tim J. McDonald, Barnett, Anna, Pearson, E, Koopman, AD, Koivula, R. W., Pearson, E., Koivula, Robert W., Heggie, Alison, McDonald, TJ, Koivula, Robert, Frost, G., Franks, PaulW., Rutters, F., Koopman, A. D., Perry, M.H., Heymans, M.W., Heggie, A, Ruetten, Hartmut, Simone Rauh, DIRECT Consortium (), Dekker, JM, Perry, MandyH., Hattersley, A., Koivula, R.W., Pearson, E. R., Franks, Paul, Herrgård, S, Franks, P. W., Vestergaard, H, Tue H. Hansen, Heymans, M. W., Koopman, AnitraD., Frost, Gary, Markku Laakso, Gary Frost, Gupta, Ramneek, Bell, J, Koopman, Anitra, Herrgård, Sanna, Teare, HJA, Dekker, Jacqueline M., Hattersley, Andrew, Hansen, Tue Haldor, Walker, M., Torben Hansen, Ridderstråle, M, Bell, Jimmy, Thorand, B, Brunak, S., Heymans, Martijn W, Søren Brunak, Laakso, M, Koopman, Anitra D., Koivisto, V., Mari, Andrea, Perry, Mandy H, Ridderstrale, M., Femke Rutters, Brunak, Soren, Pedersen, O., Hansen, Torben, Jacqueline M. Dekker, Perry, M. H., Gupta, R, Mari, A., Barbara Thorand, Teare, H. J. A., Koivisto, V, Mari, A, Dekker, JacquelineM., Koivula, RobertW., Walker, Mark, Oluf Pedersen, Franks, Paul,, Dekker, J.M., Siloaho, M, Ruetten, H., Cederberg, H, Koopman, A.D., Teare, HarrietJ.A., Pedersen, O, Dekker, J. M., Mandy H. Perry, Anitra D. Koopman, Martijn W. Heymans, Anna Barnett, Koivisto, Veikko, Laakso, Markku, Teare, H.J.A., Hansen, T. H., McDonald, TimJ., Henna Cederberg, Rauh, Simone, McDonald, Tim J, Gupta, R., Harriet J. A. Teare, Teare, H.J., Hartmut Ruetten, Jablonka, Bernd, Brunak, S, Bell, J.D., Andrew Hattersley, Franks, PW, Rutters, F, Vestergaard, Henrik, Hansen, T. V. O., Martin Ridderstråle, Robert W. Koivula, Thorand, B., Jablonka, B., Jimmy Bell, Koivula, Robert,, McDonald, Tim J., Perry, Mandy H., McDonald, Timothy J.   +176 more
core   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Regulatory T cells in the mouse hypothalamus control immune activation and ameliorate metabolic impairments in high-calorie environments

Nature Communications
The hypothalamus in the central nervous system (CNS) has important functions in controlling systemic metabolism. A calorie-rich diet triggers CNS immune activation, impairing metabolic control and promoting obesity and Type 2 Diabetes (T2D), but the ...
Maike Becker, Stefanie Kälin, Anne H. Neubig, Michael Lauber, Daria Opaleva, Hannah Hipp, Victoria K. Salb, Verena B. Ott, Beata Legutko, Roland E. Kälin, Markus Hippich, Martin G. Scherm, Lucas F. R. Nascimento, Isabelle Serr, Fabian Hosp, Alexei Nikolaev, Alma Mohebiany, Martin Krueger, Bianca Flachmeyer, Michael W. Pfaffl, Bettina Haase, Chun-Xia Yi, Sarah Dietzen, Tobias Bopp, Stephen C. Woods, Ari Waisman, Benno Weigmann, Matthias Mann, Matthias H. Tschöp, Carolin Daniel   +29 more
doaj   +1 more source

Incidence of type 1 diabetes in Australia 2000–2013 [PDF]

, 2015
Presents the latest available national data on new cases of type 1 diabetes from Australia’s National (insulin-treated) Diabetes Register. In 2013, there were 2,323 new cases of type 1 diabetes in Australia, equating to 11 cases per 100,000 population ...
Australian Institute of Health and Welfare
core  

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Robots and type 1 diabetes [PDF]

The Lancet Diabetes & Endocrinology, 2015
The robot stands about 60 cm tall . Initially, the researchers had hoped that he could engage children in general conversation. But artifi cial intelligence has not yet reached this point. “So we decided to restrict what the children did with the robot to more closed things, such as playing quizzes and little games—the robot is very good at that ...
openaire   +2 more sources

Effects of Insulin in Relatives of Patients with Type 1 Diabetes Mellitus [PDF]

, 2002
Background It is unknown whether insulin therapy can delay or prevent diabetes in nondiabetic relatives of patients with diabetes. Methods In a randomized, controlled, nonblinded clinical trial, we screened 84,228 first-degree and second-degree relatives
Group, Diabetes Prevention Trial-Type 1 Diabetes Study
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Cohort profile: the ‘Biomarkers of heterogeneity in type 1 diabetes’ study—a national prospective cohort study of clinical and metabolic phenotyping of individuals with long-standing type 1 diabetes in the Netherlands

BMJ Open
Purpose The ‘Biomarkers of heterogeneity in type 1 diabetes’ study cohort was set up to identify genetic, physiological and psychosocial factors explaining the observed heterogeneity in disease progression and the development of complications in people ...
, Erwin Birnie, Giesje Nefs, Bruce H R Wolffenbuttel, Melanie M van der Klauw, Peter R van Dijk, Klaas Hoogenberg, Henk J Veeze, Henk-Jan Aanstoot, Bruce HR Wolffenbuttel, Charlotte E Vollenbrock, Pim Dekker, Lianne S M Boesten, Martine M C de Vries-Velraeds, Adriaan Kooy, Dick Mul, Sanjoy Dutta, Rita D M Varkevisser, Michael P Brugts, Petronella H L M Duijvestijn, Christine Fransman, Rob K Gonera, Esther Latres, Sandra Loves, Theo Sas, Marleen J Vosjan-Noeverman, Rita DM Varkevisser, Lianne SM Boesten, Peter R van Dijk, Petronella HLM Duijvestijn, Martine MC de Vries-Velraeds, Melanie M van der Klauw   +31 more
doaj   +1 more source