Results 51 to 60 of about 2,364,373 (300)
Bioactive MaterialsInflammatory bowel disorders (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract (GIT). They pose significant treatment challenges due to their complex etiology.
George Chigozie Njoku +5 more
doaj +1 more source
Fulminant Type 1 Diabetes Mellitus
Endocrine Journal, 2006 Fulminant type 1 diabetes is a novel subtype characterized by a markedly rapid progression and almost complete destruction of pancreatic beta cells. The number of patients in Japan has been speculated to be 5,000-7,000. A marked decrease of beta cells in addition to alpha cells and mononuclear cell infiltration both in the endocrine and exocrine ...
Akihisa, Imagawa, Toshiaki, Hanafusa
openaire +4 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai +4 more
wiley +1 more source
Stem Cell Research & TherapyType1 Diabetes (T1D) is an autoimmune disorder characterised by the loss of pancreatic β-cells. This β cell loss occurs primarily through inflammatory pathways culminating in apoptosis.
Cathal Patrick Forkan +5 more
doaj +1 more source
Data, Data Everywhere, and Still Too Hard to Link: Insights from User Interactions with Diabetes Apps [PDF]
, 2018 For those with chronic conditions, such as Type 1 diabetes, smartphone apps offer the promise of an affordable, convenient, and personalized disease management tool. How- ever, despite significant academic research and commercial development in this area,
Blondon Katherine +8 more
core +3 more sources
Internal Medicine, 2007 To investigate clinical features and pathophysiology of a rare form of new-onset type 1 diabetes mellitus that was superimposed on established type 2 diabetes.We retrospectively analyzed 126 consecutive type 2 diabetic patients, who were admitted to the hospital 2 or more times from July 2000 to December 2005 and had been repeatedly examined for islet ...
Takahiro, Suzuki +6 more
openaire +3 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Adipose-derived mesenchymal stromal/stem cells in type 1 diabetes treatment
Communications BiologyAdipose tissue-derived mesenchymal stromal/stem cells (ADMSCs) represent a novel therapeutic intervention for Type 1 Diabetes (T1D). The attractiveness of ADMSCs is characterized by their immunomodulatory activities, regenerative properties, and relative
Vanshika Sood +7 more
doaj +1 more source
Sample size requirements for studies of treatment effects on beta-cell function in newly diagnosed type 1 diabetes. [PDF]
PLoS ONE, 2011 Preservation of β-cell function as measured by stimulated C-peptide has recently been accepted as a therapeutic target for subjects with newly diagnosed type 1 diabetes.
John M Lachin +7 more
doaj +1 more source