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Polymorphisms associated with type 1 diabetes mellitus
Background Type 1 diabetes mellitus (T1DM) is an organ-specific autoimmune disease characterized by T cell-mediated destruction of pancreatic islets. The genetic factors involved consist of at least five vulnerability genes: HLA, INS, CTLA-4, PTPN22 ...
Rachman Indra Jaya+4 more
doaj +1 more source
Update on the genetic and epigenetic etiology of gestational diabetes mellitus: a review [PDF]
Background: Many studies have been conducted on the genetic and epigenetic etiology of gestational diabetes mellitus (GDM) in the last two decades because of the diseases increasing prevalence and role in the global diabetes mellitus (DM) explosion. An update on the genetic and epigenetic etiology of GDM then becomes imperative to better understand and
arxiv
Gaussian Process-Based Model Predictive Control of Blood Glucose for Patients with Type 1 Diabetes Mellitus [PDF]
The insulin sensitivity (IS) of the human body changes with a circadian rhythm. This adds to the time-varying feature of the glucose metabolism process and places challenges on the blood glucose (BG) control of patients with Type 1 Diabetes Mellitus. This paper presents a Model Predictive Controller that takes the periodic IS into account, in order to ...
arxiv +1 more source
On the Management of Type 1 Diabetes Mellitus with IoT Devices and ML Techniques [PDF]
The purpose of this Conference is to present the main lines of base projects that are founded on research already begun in previous years. In this sense, this manuscript will present the main lines of research in Diabetes Mellitus type 1 and Machine Learning techniques in an Internet of Things environment, so that we can summarize the future lines to ...
arxiv
Cardiovascular risk in type 1 diabetes mellitus
Commonly cardiovascular risk (CVR) is linked to type 2 diabetes mellitus as this type is known to be part of the metabolic syndrome, which includes other cardiovascular factors such as hypertension, dyslipidemia.
Ines Ben Hadj Slama Slim
doaj +1 more source
Genes predisposing to type 1 diabetes mellitus and pathophysiology: a narrative review [PDF]
The possibility of targeting the causal genes along with the mechanisms of pathogenically complex diseases has led to numerous studies on the genetic etiology of some diseases. In particular, studies have added more genes to the list of type 1 diabetes mellitus (T1DM) suspect genes, necessitating an update for the interest of all stakeholders ...
arxiv
Bone remodeling in type 1 diabetes mellitus
The aim of the study is to assess the effect of changes in the body in men and women with type 1 diabetes on the state of bone mineral density and metabolic rate and determine the directionality of changes in serum markers of bone remodeling and bone ...
S. S. Safarova
doaj +1 more source
Genetics and Pathophysiology of Maturity-onset Diabetes of the Young (MODY): A Review of Current Trends [PDF]
Single gene mutations have been implicated in the pathogenesis of a form of diabetes mellitus (DM) known as the maturity-onset diabetes of the young (MODY). However, there are diverse opinions on the suspect genes and pathophysiology, necessitating the need to review and communicate the genes to raise public awareness.
arxiv
Type 1 diabetes in India: Overall insights
Type 1 diabetes mellitus (T1DM) is also on increase like type 2 diabetes, even though not in the same proportion, but still with a trend of 3-5% increase/year. India has three new cases of T1DM/100,000 children of 0-14 years.
Ashok Kumar Das
doaj +1 more source
Catalpol isolated from Rehmannia glutinosa is a potent antioxidant and investigated against many disorders. This review appraises the key molecular pathways of catalpol against diabetes mellitus and its complications.
Subrat Kumar Bhattamisra+4 more
doaj +1 more source