Results 91 to 100 of about 19,012 (177)

Lineage-specific type 1 fimbriae in hypervirulent ST23 Klebsiella pneumoniae target α3β1 integrin to promote intestinal epithelial invasion

BMC Microbiology
Hypervirulent Klebsiella pneumoniae (hvKp), particularly sequence type 23 (ST23), is a predominant global cause of pyogenic liver abscesses. While ST23 hvKp is strongly associated with this invasive pathology, the molecular basis for its enhanced gut ...
Qian Zeng, Ying Zhang, Shujing Li, Xinyue Fan, Su Wang, Jiayuan Liu, Cui Tai, Meng Li, Yuanyuan Wei, Yunkun Huang, Yi Li, Lefu Lan, Xiaofei Jiang   +12 more
doaj   +1 more source

Current Advances of Molecular Biomarkers and Liquid Biopsies Techniques in Ovarian Cancer

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Ovarian cancer (OC) remains a lethal gynecological malignancy with challenges in early diagnosis, treatment monitoring, and overcoming drug resistance. Liquid biopsy, a noninvasive approach analyzing tumor‐derived components in bodily fluids, has emerged as a promising tool in OC management.
Jingxia Zhang, Weiyan Shan, Jie Yu, Huan Shi, Qiaoping Xu, Hongkai Shang   +5 more
wiley   +1 more source

Automated Surface‐Based Segmentation of Deep Gray Matter Regions Based on Diffusion Tensor Images Reveals Unique Age Trajectories Over the Healthy Lifespan

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
This paper introduces a novel, automated deep gray matter segmentation method that relies exclusively on diffusion‐weighted imaging, eliminating the need for T1‐weighted images. When applied to a lifespan cohort from ages 5 to 90, the technique successfully mapped distinct, nonlinear developmental and aging trajectories for microstructural diffusion ...
Graham Little, J. Alejandro Acosta‐Franco, Christian Beaulieu   +2 more
wiley   +1 more source

Molecular Detection of Type 1 Fimbriae-Encoding Gene (fimH) in Uropathogenic Escherichia coli Strains Isolated from Outpatients with Urinary Tract Infection [PDF]

Journal of Fasa University of Medical Sciences, 2016
Background & Objective: Urinary Tract Infection (UTI) is one of the most common infections in all age groups. The majority of these infections are caused by Uropathogenic Escherichia coli (UPEC) strains. Colonization, attachment to uroepithelium, and the
Nemat Shams, Amin Jaydari
doaj   +1 more source

Primary Ciliary Dyskinesia: A Suggested Pathway to Transition From Pediatric to Adult Care

Pediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Primary ciliary dyskinesia (PCD) is a rare, genetically heterogeneous disorder characterized by motile ciliary dysfunction that impairs mucociliary clearance. Symptoms of PCD can include unexplained neonatal respiratory issues, chronic sino‐otopulmonary symptoms, recurrent infections, bronchiectasis, and subfertility.
Abel De Castro, Melanie Sue Collins, Raksha Jain, Jennifer B. Walsh, Juliana Alba‐Suárez, Yadira M. Rivera‐Sánchez   +5 more
wiley   +1 more source

Prevalence, distribution and genetic association of adhesin gene sequences of Escherichia coli isolates from urinary tract infections in Slovenia

Acta Biologica Slovenica, 2008
110 uropathogenic Escherichia coli (UPEC) strains obtained from the Institute of Microbiology and Immunology of the Medical Faculty in Ljubljana, Slovenia were screened with molecular biology methods for the well characterized adhesin gene sequences ...
Marjanca Starčič-Erjavec, Darja Žgur-Bertok   +1 more
doaj   +1 more source

Binding characteristics ofEscherichia colitype 1 fimbriae in the human kidney [PDF]

FEMS Microbiology Letters, 1987
Binding of the Escherichia coli type 1 fimbriae to frozen sections of human kidney was examined by indirect immunofluorescence. The purified fimbriae bound specifically to the luminal and cytoplasmic aspects of proximal tubules and to the connective tissue layer of veins and arteries. Distal tubules, collecting ducts, glomeruli and vascular endothelium
openaire   +1 more source

Deciphering the Function and Structure of PA1216 as an S‐Adenosyl‐l‐Methionine Binding Protein Using Differential Scanning Fluorimetry and Circular Dichroism

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Microbes produce bioactive secondary metabolites as toxins, pigments, or virulence factors. These specialized compounds are produced by nonribosomal peptide synthetases (NRPS), polyketide synthases (PKS), or hybrid NRPS/PKS pathways. The genes encoding NRPS and PKS reside in biosynthetic gene clusters (BGCs), some of which have no identified ...
Amaan M. Fruitwala, Jade X. Tiszler, Daniel Watson, Mansi Sinha, Tony D. Davis   +4 more
wiley   +1 more source

Nanostructured Ti–6Al–4V Reduces Adhesion of Several Bacterial Species: An In Vitro Study

Small Science, Volume 6, Issue 8, August 2026.
Alkaline etching transforms Ti–6Al–4V into nanostructured, highly hydrophilic surfaces with thicker oxide layers and selective alloy depletion. These physicochemical changes reduce early bacterial adhesion across multiple species by limiting effective nanoscale contact points, while osteoblast‐like cells retain good attachment and spreading.
Sadaf Khalatbarizamanpoor, Adrian G. Nowotnick, Stephanie Lippmann, Antje Häder, Felix Otto, Lena Raupach, Torsten Fritz, Yasmina Reisser, Jörg Bossert, Bettina Löffler, Klaus D. Jandt   +10 more
wiley   +1 more source

Unraveling the role of type 1 fimbriae in Salmonella pathogenesis: insights from a comparative analysis of Salmonella Enteritidis and Salmonella Gallinarum. [PDF]

Poult Sci, 2023
Mikolajczyk-Martinez A, Ugorski M.
europepmc   +1 more source