Results 71 to 80 of about 19,012 (177)

Orchestrated molecular changes of proliferative, migratory‐fibrillar, synaptic, and postmigratory compartments align with precocious cortex‐type specification in the early human pallium

Journal of Anatomy, EarlyView.
Early human cortical development is organized by transient cellular compartments that define cortical types before mature layers form. Analysis of the human fetal pallium (7.5–15 PCW) shows distinct spatiotemporal trajectories for the archicortex, mesocortex, and neocortex, with delayed but accelerated differentiation in allocortical regions.
Janja Kopić, Fran Božić, Alisa Junaković Munjas, Željka Krsnik, Ivica Kostović   +4 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Uropathogenic Escherichia coli P and Type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstruction. [PDF]

PLoS Pathogens, 2011
The progression of a natural bacterial infection is a dynamic process influenced by the physiological characteristics of the target organ. Recent developments in live animal imaging allow for the study of the dynamic microbe-host interplay in real-time ...
Keira Melican, Ruben M Sandoval, Abdul Kader, Lina Josefsson, George A Tanner, Bruce A Molitoris, Agneta Richter-Dahlfors   +6 more
doaj   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Antigenic relationships among type-1 fimbriae of Enterobacteriaceae revealed by immuno-electronmicroscopy [PDF]

Journal of Medical Microbiology, 1987
Antigenic relationships among type-1 fimbriae of 40 strains of Enterobacteriaceae representing 19 species and seven genera were determined by immuno-electronmicroscopy. Ten distinct antigenic groups were distinguished. Intra- and inter-generic relationships were observed although some antigenic groups were species-specific only. Antigenic relationships
R A, Adegbola, D C, Old
openaire   +2 more sources

Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications

Journal of Periodontal Research, EarlyView.
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu, Yuan Chen, Mario Romandini, Håvard Jostein Haugen, Sašo Ivanovski   +4 more
wiley   +1 more source

Activation of the NLRP3 Inflammasome Pathway by Uropathogenic Escherichia coli Is Virulence Factor-Dependent and Influences Colonization of Bladder Epithelial Cells

Frontiers in Cellular and Infection Microbiology, 2018
The NLRP3 inflammasome and IL-1β release have recently been suggested to be important for the progression of urinary tract infection (UTI). However, much is still unknown regarding the interaction of UPEC and the NLRP3 inflammasome.
Isak Demirel, Isak Demirel, Alexander Persson, Alexander Persson, Annelie Brauner, Eva Särndahl, Eva Särndahl, Robert Kruse, Robert Kruse, Robert Kruse, Katarina Persson, Katarina Persson   +11 more
doaj   +1 more source

Cutting Edge: FimH Adhesin of Type 1 Fimbriae Is a Novel TLR4 Ligand [PDF]

The Journal of Immunology, 2008
Abstract Several TLR ligands of bacterial origin induce innate immune responses. Although FimH, the adhesin portion of type 1 fimbria, plays an important role in the pathogenicity of some Gram-negative bacteria, its ability to stimulate the innate immune system via TLR signaling remains unclear.
Karen L, Mossman, M Firoz, Mian, Nicole M, Lauzon, Carlton L, Gyles, Brian, Lichty, Randy, Mackenzie, Navkiran, Gill, Ali A, Ashkar   +7 more
openaire   +2 more sources

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Phenotypic Expression of Type 1 Klebsiella pneumoniae Fimbriae in Escherichia coli HB101

مجلة مركز بحوث التقنيات الاحيائية, 2011
Four selected isolates of K. pneumoniae subsp. pneumoniae were tested for adhesion and the results revealed that isolates MK20, MK1, MK2, MK6 displayed adhesive capability with means (76.25 ± 6.0),(75.88 ± 5.13), (69.83 ± 8.43), (27.4±4.65) bacteria ...
Ehab D. Selman, Subhi J. Hamza, Meelad A. Al-Nasiri   +2 more
doaj   +1 more source